Proteins

Scientists at the University of Bath have developed a way of joining up the head and tail of a protein, making it more stable and easier to get into cells. This new tool may help researchers develop new pharmaceuticals in a cleaner, greener, and less expensive way. Drug treatments often work by binding to proteins […]

The Defense Advanced Research Projects Agency (DARPA) has announced that Ginkgo Bioworks, which is building a platform for cell programming and biosecurity, has been awarded a four-year contract worth up to $18 million to reimagine how to manufacture complex therapeutic proteins.   As a performer on DARPA’s Reimagining Protein Manufacturing (RPM) project, Ginkgo aims to […]

Today marks the start of SLAS2023 in San Diego. Over the last week, DDW’s Megan Thomas has narrated five articles from the SLAS2023 supplement as part of the DDW Events podcast series. Episodes include: A Welcome to SLAS 2023 Acquiring deeper insights and acceleration with AI Connecting lab automation to decision-making How machine learning and lab automation […]

Ahead of this year’s SLAS2023 conference in San Diego (which takes place 25 February – 1 March) DDW’s Megan Thomas narrates articles from the DDW SLAS2023 supplement as part of the DDW Events podcast series. This is episode four, How machine learning and lab automation are changing the future of protein therapeutics. In this article, […]

A project creating a new class of therapeutic proteins to modulate cell signalling has been accepted into the BioInnovation Institute (BII) Bio Studio programme. The project is based on recent breakthroughs in artificial intelligence (AI) and protein design, and uses methods pioneered by David Baker’s laboratory at the University of Washington’s Institute for Protein Design. […]

Researchers have identified the genetic links between muscle atrophy and two types of myosin, paving the way for a new disease model for scientific research and potential new treatments.  The synergistic action of the muscle proteins myosin and actin enables skeletal muscle movements. The skeletal muscle myosin heavy chain or “MyHC” is a fundamental component […]

Researchers say they have successfully used a cell’s natural process for making proteins to ‘slide’ genetic instructions into a cell and produce critical proteins missing from those cells.   If further studies verify the results, this could be a new method for targeting specific cell types for a variety of disorders that could be treated with […]

A new method to study the proteins released by cells, which could lead to new biomarkers for diseases including cancer, has been developed by scientists at the Francis Crick Institute and Imperial College London.   Biomarkers are valuable tools in diagnosing disease or predicting treatment outcomes, but they are challenging to find.  In their study, published in […]

An international team of scientists have engineered protein banana lectin, or BanLec, to create a new version that can fight off a range of viruses without unwanted side effects.  The genetically engineered version has been called H84T and worked against the viruses that cause AIDS, hepatitis C and influenza in tests in tissue and blood […]

The 2022 Protein Science in Drug Discovery ELRIG meeting will be held at The Babraham Research Campus, Cambridge UK from 2-3 November 2022. The meeting will host leading scientists from industry and academia and will aim to focus on the application of emerging areas of Protein Science to the challenges of modern drug discovery. The interactive […]

Don’t miss the opportunity to register for this exclusive DDW event High resolution electron cryo-microscopy: From membrane proteins to diseases, supported by Thermo Fisher Scientific. The webinar will take place on 19 October, 2022, 4PM BST, 8AM PDT. Discover how cryo-EM is impacting high resolution structure biology, from membrane proteins to diseases including Alzheimer’s disease and […]

Join DDW for a webinar that will demonstrate how cryo-EM is impacting high resolution structure biology from membrane proteins to diseases including Alzheimer’s disease and cancer therapeutics by showing high-resolution structures of these proteins bound to inhibitors.  The exclusive free event High resolution electron cryo-microscopy: From membrane proteins to diseases, supported by Thermo Fisher Scientific, will take […]

Join DDW for this exclusive free event High resolution electron cryo-microscopy: From membrane proteins to diseases, supported by Thermo Fisher Scientific, which will take place on 19 October, 2022, 4PM BST, 8AM PDT. Discover how cryo-EM is impacting high resolution structure biology from membrane proteins to diseases including Alzheimer’s disease and cancer therapeutics by showing high-resolution structures […]

Join DDW for this exclusive free event High resolution electron cryo-microscopy: From membrane proteins to diseases, supported by Thermo Fisher Scientific.   It will take place on 19 October, 2022, 4PM BST, 8AM PDT. Register free here.  The aim of this webinar is to demonstrate how cryo-EM is impacting high resolution structure biology from membrane proteins […]

Using deadly spider venom to treat heart attacks is one of many new discoveries currently being developed at a national research centre headquartered at The University of Queensland. The Australian Research Council (ARC) Centre of Excellence for Innovations in Peptide and Protein Science (CIPPS) was launched this week at its UQ headquarters. Researchers have found […]