Author Archives: Megan Thomas

#Covid-19 #Drug development #Pharmaceuticals #R&D

Pharmaceutical industry warned not to undo pandemic advances 

Dr Steve Arlington, President of The Pistoia Alliance, has called on the pharmaceutical industry to continue building on the advances in collaboration it has built over the past two years. Digital transformation has accelerated rapidly during the pandemic, which in turn has greatly improved remote patient monitoring, rapid online… Read More

#News

#Molecular Biology #Neuroscience #Pharmaceuticals

Novel analgesic drug is based on Nobel prize-winning discoveries 

AlzeCure Pharma says its novel clinical candidate drug ACD440 for peripheral neuropathic pain is based on the seminal discoveries of TRPV1 by Professor David Julius, for which he was awarded the Nobel Prize in Medicine 2021.  Julius, Professor and Chair of the Department of Physiology and Morris Herzstein Chair in Molecular Biology… Read More

#News

#3D modelling #Liver disease

Ready-to-go spheroids + media for drug discovery

More physiologically and pathologically relevant preclinical human liver models are needed for drug liver liability assessment and liver disease modeling. While Drug-Induced Liver Injury (DILI) remains a major safety concern, several recent high-profile NAFLD/NASH clinical trial failures further highlight this critically unmet need. With the advances in 3D culture, we… Read More

#Intelligence #Resources

#AstraZeneca #Covid-19 #Drug development #Drug discovery #Events #Immunology / Virology & Vaccines

Race against the virus: Dame Sarah Gilbert discusses her virology journey 

In late December 2019, a cluster of unusual pneumonia cases – now known to be the first human cases of Covid-19 – were reported in Wuhan, China. Due to quick action from Dame Sarah Gilbert and her team, work on the response to the new virus began. Members of… Read More

#News

#Data #Drug delivery #Lab automation #Software

Connectivity and data standards – a precondition for successful digitalisation 

  This paid-for whitepaper by The SiLA (Standardization in Lab Automation) consortium appeared in DDW Volume 22, Issue 4 – Fall 2021  R&D, manufacturing and contract research laboratories across many industries are investing in efforts to digitalise their processes and operations, with the goal of achieving end-to-end connectivity and automation. Read More

#Exclusive Content #Sponsored Content

#Biologics / Biotechnology #Cell painting #Collaboration #Drug discovery #Phenomics #Podcast

Recipe for success: collaboration in drug discovery – podcast 

The latest free-to-listen DDW podcast episode is titled “Recipe for success: collaboration in drug discovery”. It covers three articles written for Volume 22, Issue 2 – Spring 2021 of the Drug Discovery World Magazine, narrated by DDW’s Megan Thomas.  These articles are titled: “Why collaboration matters and… Read More

#Editor's Choice #News

Human liver
#3D modelling #Liver disease

Insight on ready-to-go spheroids and media for drug discovery 

More physiologically and pathologically relevant preclinical human liver models are needed for drug liver liability assessment and liver disease modeling. This app note offers insight and media for drug discovery.  While Drug-Induced Liver Injury (DILI) remains a major safety concern, several recent high-profile NAFLD/NASH clinical trial failures further… Read More

#News

#Alzheimer's #Clinical trials #Drug candidates #Drug discovery

First patients dosed in Phase I study for Alzheimer’s

AlzeCure Pharma has dosed the first patient in the company’s next clinical Phase I study (multiple ascending dose, MAD) with the candidate drug ACD856, focused on Alzheimer’s disease. ”It is satisfying that the clinical development program is proceeding according to plan and that we have now begun this follow-up Phase… Read More

#News #Trending News

Recipe for success: collaboration in drug discovery

The latest free-to-listen DDW podcast episode is titled “Recipe for success: collaboration in drug discovery”. It covers three articles written for Volume 22, Issue 2 – Spring 2021 of the Drug Discovery World Magazine, narrated by DDW’s Megan Thomas.  These articles are titled: “Why collaboration matters and… Read More

#Podcasts

Scientists in medical research lab
#Assays #Live cell analysis

New edition of Live-Cell Analysis Handbook available 

Sartorius has released the fifth edition of its Live-Cell Analysis Handbook, a reference guide for live-cell analysis technologies, focusing on the complete suite of Incucyte live-cell assays and reagents.   The live-cell applications covered in the Live-Cell Analysis Handbook include cell culture quality control assays and kinetic assays for cell health and… Read More

#News

#Biotechnology #Pharma #Pharmacovigilance #Regulatory

Listicle: Experts on the differences between FDA and EMA regulations

Biotechs involved in drug discovery have to navigate increasingly complex regulatory environments across borders. Experienced experts and non-executive advisors to Arriello, Eric Caugant, Principal Consultant at Pharmacovigilance Systems Consulting & Board advisor to Arriello, and Judi Sills, JM Sills Consulting & Board advisor to Arriello, highlight the main differences between US… Read More

#Listicles #News #Sponsored Content #Videos

#Biopharma #Cancer research #Cell therapy #Drug discovery #Flow Cytometry #Immuno-oncology #Immunology #Webinar

Deriving context from immunological data with flow cytometry – Webinar

Advances in treatments for human diseases, including cancer, rely on the ability to gain detailed information into the function, modulation, and variation of the immune system in response to stimuli or immunological challenge. Insights derived from these data have, for example, revolutionised cancer treatment by enabling the development of… Read More

#News

#Biotechnology #Collaboration #Data #Technology #Webinar

Webinar reveals how to accelerate your drug discovery program 

This free-to-watch webinar, brought to you by Certara, reviews best practices for using technology to overcome challenges in order to accelerate discovery programs.  Drug discovery research requires understanding complex chemical, biological, logistical, and computational data from a variety of data sources. A key challenge for discovery scientists is efficiently accessing the most… Read More

#Intelligence #News #Trends & Analysis

#Antibiotics #Antimicrobials #Collaboration

AMR Action Fund appointment will help with antibiotic development 

 The AMR Action Fund, a public-private partnership supporting the development of new antibiotics to address rising antimicrobial resistance (AMR), has appointed William (Bill) Burns as Board Chair.   Burns has worked in the pharmaceutical and life sciences industry throughout his life, providing invaluable experience for his role as… Read More

#News

Blood cells
#Drug development #Healthcare

Novartis update on sickle cell treatment in England and Wales 

Novartis has announced that eligible patients in England and Wales will soon have routine access to Adakveo (crizanlizumab) under a Managed Access Agreement (MAA), which the company says not only helps with sickle cell disease (SCD), but also demonstrates a commitment to supporting health equity for a community that has been historically underserved,… Read More

#News