A new international has shown that treating critically ill patients with COVID-19 with the steroid hydrocortisone improves their chances of recovery. The study, led in the UK by Professor Anthony Gordon from Imperial College London with collaborators from the Intensive Care National Audit & Research Centre, found that patients receiving intensive care who were treated […]

While everyone’s attention is focused on efforts to contain COVID-19, few probably noticed signs that the UK health system is about to undergo some major changes that will have an impact on both patients and the healthcare industry as early as next year. In preparation for the end of the Brexit transition period, the UK government […]

Oxford Biomedica has signed an 18 month supply agreement with AstraZeneca UK for large-scale commercial manufacture of the adenovirus vector-based COVID-19 vaccine candidate, AZD1222. The supply period for AZD1222 may be extended by a further 18 months into 2022 and 2023 by mutual agreement. AstraZeneca will pay Oxford Biomedica £15million upfront as a capacity reservation […]

By Ibis Sanchez-Serrano and Rathnam Chaguturu Mitigation of COVID-19 pandemic requires a combination of effective epidemiological policies and the discovery/development of powerful drugs against the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) that causes this disease. This article examines the major initiatives being explored at the public policy level to contain the spread of COVID-19 […]

NIAID intends to provide approximately $82 million over five years to support the network. The National Institute of Allergy and Infectious Diseases (NIAID), in the US, has awarded 11 grants with a total first-year value of approximately $17 million to establish the Centers for Research in Emerging Infectious Diseases (CREID). The global network will involve […]

Dotmatics has launched Bioregister 2020.1, the latest version of its web-based application for registering sequence-based, chemically modified and structure-less biological entities. The enhanced application will support researchers developing chemically-modified therapeutics for drug discovery, by allowing users to define entities with full chemical representation and use that chemical representation for uniqueness checking during registration. Bioregister 2020.1 […]

The Medicines and Healthcare products Agency (MHRA) has approved the trial following new preclinical research that suggests a glucose kinase activator (AZD1656) could help diabetes sufferers infected with coronavirus by dampening the overactive response of the immune system typically acute in those patients with raised blood glucose levels. The trial will involve hospitalised patients with […]

Mitigation of COVID-19 pandemic requires a combination of effective epidemiological policies and the discovery/development of powerful drugs against the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) that causes this disease. This two part article series examines the major initiatives being explored at the public policy level to contain the spread of COVID-19 as well as […]

The first participants have been dosed in a Phase I trial of AZD7442, a combination of two monoclonal antibodies (mAbs) in development for the prevention and treatment of COVID-19. The trial will evaluate the safety, tolerability and pharmacokinetics of AZD7442.1 The trial will include up to 48 healthy participants in the UK aged 18 to […]

SLAS2021 will take place virtually, but still offers the opportunity to share research and connect with life sciences professionals around the globe. The schedule of events has been designed to enable a broad global attendance and the digital platform aims to support participant engagement with speakers, vendors and poster presenters. The event, which will take […]