News round-up for 24 – 28 November by Bruno Quinney, Content Team at DDW. 

This week in drug discovery, gene therapies are providing solutions for complex conditions, most notably in Hunter syndrome but also in amyotrophic lateral sclerosis. Elsewhere, an antibody-drug conjugate precision therapy could prevent breast cancer. 

The top stories: 

 

Revolutionary therapy treats Hunter syndrome for the first time 

A world-first therapy has provided an unprecedented step towards treating the devastating condition Hunter syndrome. 

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RNA-based gene therapy offers new hope for ALS treatment 

A team of researchers have uncovered a previously unknown molecular mechanism that drives the progression of amyotrophic lateral sclerosis (ALS) and succeeded in neutralising it using RNA-based gene therapy.   

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ADC precision therapy could prevent breast cancer, study shows 

Researchers at the University of California San Diego School of Medicine used an antibody-drug conjugate (ADC) to target a cell-surface protein known as FZD7. 

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Study shows how water influences cancer drug potency 

Researchers have demonstrated how computational simulations can unravel the complex role of water molecules in drug binding. 

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DDW Turning Science into Business Symposium available on demand 

The event features talks covering aspects of drug discovery including AI, oncology, CRISPR, neuroscience and more.  

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