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        Janssen

        Vaccine

        Experimental HIV vaccine safe but ineffective

        20 January 2023

        An investigational HIV vaccine regimen was safe but did not provide protection against HIV, an independent data and safety monitoring board (DSMB) has determined.  The regimen was tested among men who have sex with men (MSM) and transgender people. The HPX3002/HVTN 706, or ‘Mosaico’, Phase III clinical trial began in 2019 and involved 3,900 volunteers […]

        Myeloma cells

        Janssen seeks European approval for multiple myeloma drug

        3 January 2023

        Janssen has submitted a marketing authorisation application (MAA) seeking approval of talquetamab in Europe for the treatment of patients with relapsed or refractory multiple myeloma (RRMM).   Talquetamab is an investigational, off-the-shelf, bispecific T-cell engager antibody targeting both GPRC5D, a novel drug target that is on some normal cells but overexpressed on myeloma cells, and CD3 […]

        Scientist in laboratory

        New trial data revealed in potential myeloma and leukaemia treatments

        16 December 2022

        Jannsen has revealed clinical trial results for its pipeline of products to treat multiple myeloma and leukaemia.  The findings were presented at the American Society of Hematology (ASH) 2022 Annual Meeting taking place in New Orleans, US.  Along with positive Phase II trial data for talquetamab, the company presented promising findings on the long-term results […]

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