Immunology

This paid-for advertorial by Sphere Fluidics appeared in the SLAS 2023 Supplement, Volume 24 – Issue 1, Winter 2022/2023 Modern drug development has expanded from chemist-made substances to biologics and cell-based therapies. Despite the progress of the last two decades, we are only scratching the surface of what is possible and beginning to understand the underlying […]

Dr Amber Miller, Flow Cytometry Scientist, Fortis Life Sciences, says flow cytometry techniques can help our understanding of cancer associated fibroblasts but there is still work to be done. Inside any solid tumour there is high heterogeneity, and the types of tumour cells, immune cells, and stromal cells present and their functional states dictate disease severity […]

Here, we speak with two of the keynote speakers at this year’s Drug Discovery 2022, Molly Stevens, Professor of Biomedical Materials and Regenerative Medicine at Imperial College London, and Rab Prinjha, VP Head of Immunology Research Unit at GlaxoSmithKline, about the insights they will be sharing and what they see as the drivers of the drug discovery […]

As experimental data becomes bigger and more complex, scientists are challenged to make discoveries faster, consistently document and analyse their work, and easily collaborate across an organisation and with external partners. Electronic lab notebooks (ELN) provide access to all collaborators 24/7, wherever they are and whether they are employees or at contract organisations. If an […]

Mouse models with human immune cell engraftment provide platforms to evaluate compounds to treat a variety of human diseases. Humanised PBMC (hu-PBMC) mice feature quick engraftment of adult peripheral blood mononuclear cells and enable short-term studies requiring mature human T cells. Hu-PBMC mice are used as in vivo models to study and evaluate compounds for […]

This whitepaper, brought to you by The Jackson Laboratory will teach: The benefits of the JAX NSGTM-MHC I/II KO mouse platform humanised with pre-characterised PBMCs How this platform can support a wide range of immunological studies, especially those containing T cells responses The versatility of this platform to various research disciplines

Professor Dr Cornelis (‘Kees’) Melief has been awarded the 2022 Pedro J Romero Service to JITC Award by the Society for Immunotherapy of Cancer (SITC).  The Award recognises individuals who have made immeasurable contributions and demonstrated outstanding commitment to the Journal for Immunotherapy of Cancer (JITC) and will be presented at the SITC’s 37th Annual […]

Researchers at the Francis Crick Institute in the UK, have shown that a specific area of the SARS-CoV-2 spike protein is a promising target for a pan-coronavirus vaccine that could offer some protection against new virus variants, common colds, and help prepare for future pandemics. Developing a vaccine that provides protection against a number of […]

Amphista Therapeutics, a company focused on the development of next generation targeted protein degradation (TPD) therapeutics, has signed a strategic collaboration and license agreement with Bristol Myers Squibb.   The companies will work together to discover and develop small molecule protein degraders. Bristol Myers Squibb will be granted a global exclusive license to the degraders developed and will […]

Chiedzo Mpofu, Vice President, Global Medical Affairs Head, Immunology, at AbbVie, talks to Lu Rahman about our understanding of auto-immune disease and how AbbVie is continuing to innovate in this field. “Immune mediated diseases are a diverse group of conditions that share common inflammatory pathways,” says Chiedzo Mpofu, Vice President, Global Medical Affairs Head, Immunology, […]