Flagship Pioneering

#Flagship Pioneering #Foundational model #Start-ups #Transcriptomics

New company Etcelera unites three drug discovery platforms

Flagship Pioneering has announced the formation of Etcelera, a company created by the merger of the platforms of Cellarity, Etiome and Empress Therapeutics.  The new company aims to pioneer causal intelligence in human biology: the ability to determine what truly drives disease and predict how a medicine… Read More

#Business & Investment #News #Start-up Zone

Neural networks
#Artificial intelligence (AI) #Flagship Pioneering #Small molecules

Flagship Pioneering unveils $50 million AI platform

Biotechnology company Flagship Pioneering has unveiled its generative AI platform Expedition Medicines, backed by $50 million in funding.  Flagship believes Expedition Medicines will push the boundaries in medicine to enable the creation of first-in-class therapies across oncology, immunology and other diseases. The platform can learn the rules… Read More

#Business & Investment #News

Transfer RNA
#Alltrna #Flagship Pioneering #Mouse models #Oligonucleotides #Rare disease #RNA #tRNA

First tRNA development candidate restores protein production

Data demonstrate that engineered tRNA from Alltrna’s first development candidate restores protein production to clinically meaningful levels in two disease models driven by the same premature termination codon.  AP003 is a chemically modified, engineered tRNA oligonucleotide in a clinically validated, liver-directed lipid nanoparticle (LNP) that can readthrough… Read More

#News

#Cardiovascular disease #Collaboration #Drug discovery #Flagship Pioneering #Partnership #Pfizer

Flagship and Quotient partner on cardiovascular disease therapies

Pfizer has expanded its strategic partnership with Flagship Pioneering, adding two new research programmes with Flagship-founded Quotient Therapeutics. Under the collaboration, the companies will analyse somatic mutations that occur in diseased patient tissue to inform the discovery and development of therapies for cardiovascular and renal diseases. Read More

#Business & Investment #News

Weight loss and obesity
#Collaboration #Flagship Pioneering #Obesity #Pfizer #ProFound Therapeutics

Breakthrough drug discovery research collaboration in obesity

Flagship Pioneering and ProFound Therapeutics have announced a collaboration to conduct foundational research to identify potential next-generation first-in-class therapies for the treatment of obesity. The collaboration is the first initiated under Flagship’s Pioneering Medicines strategic partnership with Pfizer announced in July 2023. Pioneering Medicines,… Read More

#News