DNA

Cancers can evolve to become more aggressive without relying only on DNA mutations, two major studies have revealed.  The research characterises an extra level of control of cancer gene activity within tumours, which the researchers describe as cancer’s ‘dark matter’.  The two studies showed how a level of gene control called ‘epigenetics’ plays a central […]

Yapan Bio has expanded its capabilities with a new process development facility at Genome Valley, Hyderabad, India, which has enhanced its ability to support end-to-end development and manufacturing of RNA, DNA and gene therapy products starting from plasmids.   The expansion includes three upstream suites (including Bio-Safety Level-2 containment), a downstream process development lab, an analytical […]

A team of researchers at Northwestern University in the US has devised a new platform for gene editing that could inform the future application of CRISPR-based therapeutics. Using chemical design and synthesis, the team brought together the Nobel-prize winning technology with therapeutic technology born in their own lab to overcome a critical limitation of CRISPR.  […]

Beckman Coulter Life Sciences has released a call for registrations for its SPRI Grants for Genomic Research, which the company describes as part of its commitment to the next generation of researchers and scientists.  Reinforcing its dedication to providing streamlined genomic workflow solutions, the company will award up to eight grants in 2022. The grants […]

This e-book, sponsored by Evonetix, contains exclusive insight from industry experts on how synthetic biology is innovating and advancing drug discovery.   Key topics include:   Four key approaches to synthetic biology  The global advances in synthetic biology drug discovery Why synthetic biology is the next big step for biopharma  What an organoid innovation centre means for 3D biology […]

Evonetix is reimaging biology by developing a different approach to gene synthesis. Three key members of the team – Dr Raquel Sanches-Kuiper, Vice President of Technology, Dr Matthew Hayes, Chief Technology Officer and John Edgell, Head of Cloud Engineering – explain how the company is doing this and what it means for the advancement of […]

News round-up by DDW’s Reece Armstrong for 18 – 22 July Covid-19 vaccines remain effective six months after second dose  Two doses of Covid-19 vaccines were sufficient in providing protection against severe cases of the infectious disease, according to new research.   New combination therapy shows promise against lung cancers   Scientists have discovered a new combination […]

Non-coding or ‘junk’ DNA could contribute to the development of certain cancers due to how it disrupts the replication of the genome, scientists have discovered.   A team from The Institute of Cancer Research (ICR), London reconstituted the entire process of DNA replication in a test tube in order to understand it more completely.  The team […]

By Dr. Oyvind Dahle and Michael R.Pontrelli, Foley & Lardner LLP. The first complete, gapless sequence of a human genome was published 1 April 2022 in a special issue of the journal Science1. While The Human Genome Project mapped about 92% of the human genome two decades ago, sequencing the last 8% of the genome […]

Research from the University of Birmingham in the UK has indicated that a cancer therapy could help damaged nerves repair themselves following spinal injury.   The research shows that AstraZeneca’s candidate drug AZD1390 can block the response to DNA damage in nerve cells and promote regeneration of damaged nerves, restoring sensory and motor function after spinal […]