Cellular assays

#Cellular assays #High Throughput #Semarion

Semarion raises $3.8m to scale cell assay technology 

Semarion has raised $3.8 million to scale its next-generation cell assay technology and expand manufacturing of its microcarrier platform.  The company, a University of Cambridge spin-out from the Cambridge Laboratory, will use investment to facilitate commercial expansion and scale manufacturing of its SemaCyte platform, which enables adherent cell models to be… Read More

#Business & Investment #News

amino acids chain
#Cellular assays #Promega #SLAS2026

Promega launches cellular target engagement platform 

Promega has launched a new live-cell target engagement platform aiming to close a long-standing gap between biochemical and cellular assays for understudied or difficult-to-interrogate proteins.  TheTarSeer BRETSA Target Engagement System is a novel bioluminescence resonance energy transfer-based shift assay for detecting ligand-protein interactions in intact cells using protein denaturation. … Read More

#News

Automated liquid handling
#Automation / robotics #Cellular assays #Collaboration #Drug discovery #Semarion #SPT Labtech

SPT Labtech and Semarion partner on automated cell-based discovery

SPT Labtech and Semarion, a University of Cambridge spin-out company from the Cavendish Laboratory, have announced a strategic collaboration.   The partnership will integrate SPT Labtech’s firefly liquid handling platform with Semarion’s SemaCyte microcarrier technology to develop an automated workflow to simplify and accelerate key stages of adherent… Read More

#Business & Investment #News

Scientist pipetting in the lab
#Cellular assays #Drug discovery #Interview #Screening #Spinout #Turning Science into Business

Turning science into business: A step-change in adherent cell-based assays

Semarion was voted one of the SLAS2025 New Product Award winners. DDW’s Diana Spencer catches up with CEO and Co-founder Jeroen Verheyen to find out how the company has bridged the worlds of science and engineering.  DS: Congratulations on being one of the SLAS2025 New Product Award winners. Read More

#Business & Investment #Exclusive Content

#Automated workflows #Automation #Automation / robotics #Case study #Cell and gene therapy #Cellular assays #Viral vectors

Case study: Automating cell-based assays

A new Case Study is now available to download from Hamilton. Oxford Biomedica is an innovative leading viral vector specialist focused on delivering life-changing therapies to patients. The company works across key viral vector delivery systems (lentiviral-, adeno-associated viral- and adenoviral-based vector systems), providing innovative solutions to cell and gene… Read More

#News

#Automated workflows #Automation #Automation / robotics #Cell and gene therapy #Cellular assays #Viral vectors

Automating cell-based assays to determine viral vector titer

In this Case Study, Oxford Biomedica, an innovative global gene and cell therapy company, describes: The automated system used for a 10-day cell-based workflow required for an analytical test to determine viral vector titer The advantages of Hamilton’s CECULA Graphical User Interface (GUI) for the planning of long-term cell-based assays… Read More

#Resources

#Assay development optimisation & technology #Assay validation #Assays #Cellular assays #In vitro assays

Assays: A key ingredient to success in drug discovery

DDW’s Megan Thomas discusses the value of assays and their influence across the drug discovery sector. Assays are a critical part of drug discovery, providing various means to measure biological or biochemical activity of potential drug compounds. Across the sector, it is evident the impact they have and their inherent… Read More

#Exclusive Content

High-throughput screening
#Assays #Cell / tissue culture #Cellular assays #Drug discovery #eBook #High throughput screening

Overcome the challenges of cell-based high-throughput screening

The tenth eBook of the Hamilton series is now available to download, entitled ‘Cell-Based High-Throughput Screening‘. The eBook covers: Cell-based models used in research – pros and cons. Challenges of cell-based high-throughput screening. Hamilton software and hardware tools for cell-based assays. Download now. Read More

#News

#Assays #Cell / tissue culture #Cellular assays #Drug discovery #High throughput screening

Cell-Based High-Throughput Screening

In the tenth eBook of the Hamilton series, ‘Cell-Based High-Throughput Screening’, we discuss: Cell-based models used in research – pros and cons. Challenges of cell-based high-throughput screening. Hamilton software and hardware tools for cell-based assays. Read More

#Resources

#ADME / Tox #Cellular assays #Drug toxicity #Market reporting #Omics #Toxicology

Late-stage drug failures drive toxicology testing market growth

The global ADME toxicology testing market is predicted to generate a revenue of $19.21 billion by 2030, with a growth rate of 10.2%. Factors such as an increased need to check late-stage drug failures with the adoption of more appropriate toxicity testing methods by pharmaceutical companies… Read More

#Business & Investment #News

Two scientists in a research laboratory
#App note #Artificial intelligence (AI) #Assays #Cell culture #Cellular assays #Cellular imaging

Discover how to streamline migration assays with in-incubator monitoring

Cell migration assays can be time-consuming and challenging, from identifying and ensuring assays are imaged at the appropriate time, to properly measuring wound closure. In this new App Note, discover the benefits of Evident’s CM cell culture monitors, which provide label-free, quantitative results, consistent results throughout your lab, and are… Read More

#News

#Artificial intelligence (AI) #Assays #Cell culture #Cellular assays #Cellular imaging

Streamline migration assays with in-incubator monitoring

Cell migration assays can be time-consuming and challenging, from identifying and ensuring assays are imaged at the appropriate time, to properly measuring wound closure. Evident’s CM cell culture monitors provide label-free, quantitative results, consistent results throughout your lab, and are cost-effective. Researchers at ACEL simplified the cell migration process by… Read More

#Resources

Animal testing
#Animal models #Animal testing #Cellular assays #FDA #Organoids #Preclinical investigations

FDA Modernization Act 2.0: A step in the right direction

By DDW Editor Reece Armstrong A lot has already been said about the US Food and Drug Administration’s (FDA) Modernization Act 2.0 and for good reason. The decision by the Biden administration to end the federal requirement for drugs under development to be tested on animals represents a significant step forward for the… Read More

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#AI / data analytics / healthtech / informatics #Analysis #Assay development optimisation & technology #Automation / robotics #Biomarkers #Cellular & Molecular biology #Cellular assays #Clinical specialities #Clinical trials #Drug development #Drug discovery #Drug targets #Enabling technologies #Genetics / genomes #High Content Screening #High throughput screening #Imaging #Immunology #Immunology / Virology & Vaccines #Lead discovery #Microbiology #Molecular medicine #Protein chemistry / Proteomics #RNA #Screening #Stem cells #System biology #Systems biology #Therapeutics #Toxicology

High content screening in action: a powerful tool to identify novel antivirals and vaccines

By Dr Karin Bottcher High content screening (HCS) has played a significant role in infectious disease research and drug discovery to date and can be a strong tool in the age of COVID-19 and beyond. With a focus on viral diseases, this article… Read More

#Covid-19 #Exclusive Content

#AI / data analytics / healthtech / informatics #Analysis #Animal models #Assay development optimisation & technology #Automation / robotics #Business #Cell therapy #Cellular & Molecular biology #Cellular assays #Chemical engineering #Chemistry #Clinical specialities #Clinical trials #Computational chemistry #Drug development #Drug discovery #Gene therapy #Genomics #High Content Screening #High throughput screening #Immunology / Virology & Vaccines #Lead discovery #Lead optimisation #Mass spectrometry / NMR #Medicinal chemistry #Molecular medicine #Organic chemistry #Pharmokinetics #Precision medicine #RNA #Screening #System biology #Systems biology #Therapeutics #Toxicology

The COVID-19 antiviral race: we’re all in this together

The COVID-19 antiviral race: we’re all in this together By Uduak Grace Thomas In response to the COVID-19 pandemic, international scientists from academia and industry have pooled their expertise and resources to identify candidate compounds that inhibit the activity of the SARS-CoV-2 main protease, in order to develop… Read More

#Covid-19 #Exclusive Content

#Academic #AI / data analytics / healthtech / informatics #Animal models #Assay development optimisation & technology #Automation / robotics #Biomarkers #Business #Cell / tissue culture #Cell culture #Cellular assays #Clinical specialities #Clinical trials #Drug development #Drug discovery #Drug targets #Enabling technologies #High Content Screening #High throughput screening #Imaging #Lead discovery #Pharmokinetics #Preclinical #RNA #Screening #Stem cells #System biology #Systems biology #Target validation #Therapeutics #Toxicology #Translational #Translational chemistry

The CELL CULTURE innovations increasing drug discovery success

The CELL CULTURE innovations increasing drug discovery success By Helen Stewart-Miller and Abby George Volume 21 Issue 3 – Summer 2020 ‘Fail early, fail fast’ has been a mantra in the pharmaceutical industry for several years and directly impacts the overall strategy of many drug discovery and development… Read More

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