Cell therapy

Cobra Biologics, the gene therapy division of the Cognate BioServices’ group, has announced a multi-phase expansion of its plasmid DNA services, a continuation of its gene therapy services’ project for viral vectors and plasmid DNA. This includes a four-fold increase in HQ High Quality (HQ) DNA manufacturing capacity alongside new clinical and commercial GMP DNA […]

The Cell and Gene Therapy Catapult (CGT Catapult) and Hertfordshire Local Enterprise Partnership (LEP) in the UK have announced that a new cell and gene therapy integration laboratory at the CGT Catapult facility in Stevenage will be part-funded by the government’s Getting Building Fund. The new laboratory will be exclusively dedicated to the provision of […]

Cedars-Sinai has launched a centre to manufacture the next generation of stem cell and gene therapies that will enable biomedical researchers, government medical programs, commercial entities and others to develop new biologic drugs and propel novel disease discoveries. Biologic drugs are produced from living organisms or contain components of living organisms, such as cells, proteins […]

The Jefferies Healthcare Temperature Check report is now in its third edition and published to coincide with the 11th annual Global Healthcare Conference which was held virtually. Over 500 responses from senior leaders in the sector responded for this year’s report, giving views on both the current state of the market and predictions for 2021. […]

Lonza will be hosting a free webinar to discuss its innovative approach to digitalising the company’s cell and gene therapy manufacturing operations through the implementation of the MODA-ESTM Platform. It will take place on 17 November. In the webinar, Lonza will also outline future plans for utilising the platform to eliminate bottlenecks and achieve operational […]

Bone Therapeutics, the cell therapy company and Catalent Pharma Solutions, provider of advanced delivery technologies, development, and manufacturing solutions for drugs, biologics, cell and gene therapies have announced the signing of share purchase and supply agreements. The agreements will streamline and economise the manufacturing operations of ALLOB, Bone Therapeutics’ allogeneic cell therapy product and will […]

Bayer has acquired Asklepios BioPharmaceutical (AskBio) a US-headquartered biopharmaceutical company specialising in the research, development and manufacturing of gene therapies across different therapeutic areas. AskBio’s development portfolio includes investigational pre-clinical and clinical stage candidates for the treatment of neuromuscular, central nervous system, cardiovascular and metabolic diseases. Bayer will own full rights to AskBio’sgene therapy platform, […]

Mogrify’s EpiMOGRIFY platform models the epigenetic state of the cell to predict the switches important for cell identity, cell maintenance, directed differentiation and cell conversion. EpiMOGRIFY is an extension of the company’s proprietary direct cellular conversion technology, MOGRIFY, and enables the identification of the optimal culture conditions required to maintain cells in chemically defined media. This […]

The UK Department for International Trade (DIT) has classified Stevenage in the UK, as a High Potential Opportunity (HPO) zone in recognition of its thriving cell and gene therapy cluster of national and international significance. The successful HPO nomination was made by Hertfordshire Local Enterprise Partnership (LEP) and is expected to help attract further overseas […]

Absorption Systems works collaboratively with biotech and pharma companies. Dealing with their future therapeutics, the company’s analytical research services help customers streamline and simplify the approval process. Lu Rahman found out more from CEO Patrick Dentinger. LR: Describe Absorption Systems’ analytical testing expertise in relation to cell and gene therapy PD: As an analytical lab, customers […]

CPhI Annual Report 2020 highlights cell and gene therapy capacity shortages in the USA and 10+ mAb approvals in China. Continuous Bioprocessing growing quickly, but from a low base, with virtually all manufacturers now using at least some single use technologies. CPhI Annual Report – launched ahead of the first CPhI Festival of Pharma (5-16 […]

The International Society for Cell & Gene Therapy (ISCT) has a vision – to translate cell and gene research into safe and effective therapies to improve patients’ lives worldwide. Queenie Jang, CEO, explains…. Established in 1992, the ISCT  is a global society of over 2300 clinicians, regulators, researchers, technologists and industry partners. Driven by volunteer leaders […]

By Ibis Sanchez-Serrano and Rathnam Chaguturu Mitigation of COVID-19 pandemic requires a combination of effective epidemiological policies and the discovery/development of powerful drugs against the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) that causes this disease. This article examines the major initiatives being explored at the public policy level to contain the spread of COVID-19 […]

By Dr Jamie Freeman Base editing is a potentially transformative technology for engineering DNA in cells that has the potential to generate knockouts or correct certain errors or mutations in the DNA for applications such as cell or gene therapies. Compared with currently-available gene editing methodologies such as CRISPR/Cas9, which creates ‘cuts’ in the gene […]

By Dr Ross Macdonald Cell-based therapies are being widely recognised for their potential to treat a variety of medical conditions, but they face major obstacles toward commercialisation. Traditionally, they have been difficult and expensive to make in large quantities. Biopharmaceutical companies must develop manufacturing solutions that will enable them to efficiently and reproducibly create the […]

Honing in on perfect targeting By Dr Samantha Zaroff Volume 21 Issue 3 – Summer 2020 The pros and cons of different delivery modalities for personalised cancer vaccines. Introducing neoantigens directly into a patient in order to elicit an anti-tumour killing immune response is known as personalised cancer vaccine therapy. Currently, there is a huge […]