Cancer research

Cancer cell
#AACR 2023 #Cancer research #CAR-T #DDW Events podcast #Meet the Researcher #T cell receptor (TCR) #Triumvira Immunologics

DDW Events: AACR 2023 Episode 3 with Vito Palombella, Surface Oncology

At the American Association of Cancer Research’s Annual Meeting in Orlando, Florida, DDW’s Megan Thomas met with industry experts to learn more about their research and careers in the field of cancer research. In this latest episode, Thomas speaks with Vito Palombella, Chief Scientific Officer at Surface Oncology. You… Read More

#Podcasts

Cancer cells
#American Society of Clinical Oncology #Breast cancer #Cancer research #HER2 #Oncology #The College of American Pathologists

Updates to HER2 testing guidelines reduces confusion 

The College of American Pathologists (CAP) and American Society of Clinical Oncology (ASCO) have reaffirmed the Human Epidermal Growth Factor Receptor 2 (HER2) Breast Cancer Testing Guidelines, reducing confusion over terminology for reporting HER2 results.  The recent clinical trial for metastatic breast cancer patients (DESTINY-Breast04) found that a treatment traditionally… Read More

#Cancer Research #News #Regulatory #Trending News

#AACR 2023 #Cancer research #CAR-T #DDW Events podcast #Meet the Researcher #T cell receptor (TCR) #Triumvira Immunologics

Meet the researcher: Andreas Bader, Triumvira Immunologics

At the American Association of Cancer Research’s Annual Meeting in Orlando, Florida, DDW's Megan Thomas met with industry experts to learn more about their research and careers in the field of cancer research. Thomas speaks with Andreas Bader, Chief Scientific Officer at Triumvira Immunologics. MT: Where do you work, and… Read More

#Cancer Research #Exclusive Content #Opinion

Cancer cells
#AACR 2023 #Cancer research #CAR-T #DDW Events podcast #Meet the Researcher #T cell receptor (TCR) #Triumvira Immunologics

DDW Events: AACR 2023 Episode 2 with Andreas Bader, Triumvira Immunologics

At the American Association of Cancer Research’s Annual Meeting in Orlando, Florida, DDW’s Megan Thomas met with industry experts to learn more about their research and careers in the field of cancer research. In this latest episode, Thomas speaks with Andreas Bader, Chief Scientific Officer at Triumvira Immunologics. You… Read More

#Podcasts

Cancer cell
#Cancer research #Chemotherapy #Drug development #National Institute for Health and Care Excellence (NICE) #Regulatory

Positive NICE recommendation for BRCAm ovarian cancer 

AstraZeneca UK announced that Lynparza (olaparib) is recommended by the National Institute for Health and Care Excellence (NICE) for maintenance treatment of BRCA-mutated relapsed, platinum-sensitive, high-grade epithelial ovarian, fallopian tube, or primary peritoneal cancer in adults who have had two or more courses of platinum-based chemotherapy.  BRCA1 and BRCA2 are… Read More

#Editor's Choice #News #Regulatory #Trending News

#Cancer research #Clinical trial design #Clinical trials #FDA #Phase I trial

New DDW Highlights podcast for 12 June 2023

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates.  There has been some interesting news related to clinical trials this week, with the announcement that… Read More

#News

Cancer cells
#AACR 2023 #Cancer research #DDW Events podcast #Kintara Therapeutics #Meet the Researcher #Therapeutics

DDW Events: AACR 2023 Episode 1 with Dennis Brown, Kintara Therapeutics

At the American Association of Cancer Research’s Annual Meeting in Orlando, Florida, DDW’s Megan Thomas met with industry experts to learn more about their research and careers in the field of cancer research. In this latest episode, Thomas speaks with Dennis Brown, Chief Scientific Officer at Kintara Therapeutics. You… Read More

#Podcasts

#AACR 2023 #Cancer research #DDW Events podcast #Kintara Therapeutics #Meet the Researcher #Therapeutics

Meet the researcher: Dennis Brown, Kintara Therapeutics 

At the American Association of Cancer Research’s Annual Meeting in Orlando, Florida, DDW's Megan Thomas met with industry experts to learn more about their research and careers in the field of cancer research. Thomas speaks with Dennis Brown, Chief Scientific Officer at Kintara Therapeutics. You can also listen to these… Read More

#Cancer Research #Exclusive Content #Opinion

Audience
#ASCO #Cancer research #Immutep #Oncology #Phase II trial

Immutep reports positive final data at ASCO 2023

Immutep revealed positive final data from Part C of the TACTI-002 Phase II trial at the ASCO 2023 Annual Meeting in Chicago, US. The trial evaluated eftilagimod alpha (efti), a soluble LAG-3 protein and first-in-class MHC Class II agonist, in combination with MSD’s (Merck) anti-PD-1 therapy Keytruda… Read More

#Cancer Research #News

#Cancer research #Clinical trial design #Clinical trials #FDA #Phase I trial

This week in drug discovery (5-9 June)

News round-up for 5-9 June by DDW Digital Content Editor Diana Spencer. There has been some interesting news related to clinical trials this week, with the announcement that the FDA has published draft guidance to modernise the design and conduct of studies, and the failure of… Read More

#News

Bladder
#ASCO #Cancer research #Clinical trial #Oncology #RemeGen

Promising results for disitamab vedotin in bladder cancer

RemeGen announced the latest clinical research results on disitamab vedotin (RC48) at the 2023 American Society of Clinical Oncology (ASCO) Annual Meeting. Researchers tested disitamab vedotin and toripalimab in combination on patients diagnosed with locally advanced or metastatic urothelial carcinoma (la/mUC). The objective of the study… Read More

#Cancer Research #News

Antibodies attack cancer cell
#ASCO #Cancer research #Clinical trials #Events #Oncology

Four breakthroughs in cancer research revealed at ASCO 2023

Ground-breaking data from several key cancer trials were announced at the American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago. ADAURA Phase III trial The trial assessed Tagrisso (osimertinib) as an adjuvant treatment of patients with early-stage (IB, II and IIIA) epidermal growth factor receptor-mutated… Read More

#Cancer Research #News #Trending News

Chemistry
#Cancer research #Click chemistry #Johnson & Johnson #Oncology #Partnership #Shasqi

Partners will use click chemistry to create targeted cancer therapies

Biotech company Shasqi and Johnson & Johnson have entered into a research collaboration to develop new cancer therapies. Shasqi’s Click Activated Protodrugs Against Cancer (CAPAC) platform relies on chemistry for activation of drugs at the tumour. The platform is made up of a tumour-targeting agent and… Read More

#Cancer Research #News

Breast cancer
#ASCO #Breast cancer #Cancer research #Novartis #Oncology #Phase III trial

Drug reduced the risk of breast cancer recurrence by 25%

Positive primary endpoint data from Novartis’ pivotal Phase III NATALEE trial has been presented at the 2023 American Society of Clinical Oncology (ASCO) Annual Meeting. Data showed that Kisqali (ribociclib) plus endocrine therapy (ET), compared to ET alone, lowered the risk of cancer recurrence by 25.2%… Read More

#Cancer Research #News #Trending News

Laboratory research
#Antibody #ASCO #Cancer research #Clinical trials #Immunotherapy #Janssen #Oncology #T cell activation

Janssen updates ASCO 2023 on oncology pipeline

Janssen has presented new data from across its oncology pipeline at the American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago. Talquetamab Talquetamab is an investigational GPRC5D-directed bispecific antibody currently in clinical development. Updated results from the Phase II MonumenTAL-1 study show that… Read More

#Cancer Research #News #Trending News

#Cancer research #Macomics #Macrophages #Omics #Oncology #Tumour microenvironment (TME) #Turning Science into Business

Turning science into business: Exploiting macrophage biology

DDW’s Diana Spencer chats to Macomics’ co-founder and VP Immunology Dr Luca Cassetta about the company’s approach to tumour suppression and the challenges of launching a new business in early 2020. DS: Congratulations on the publication of your discoveries in Nature Reviews Cancer. Your studies focus on tumour associated macrophages (TAMs). What role do they… Read More

#Cancer Research #Exclusive Content