Bioscience

Vésale Bioscience, a company in the research and development of solutions and treatments using phage therapy for multi-resistant infections, has received €1.8 million in grants from the European Innovation Council (EIC) Accelerator Fund for its PhageDiag project.  The project is a phagogram using artificial intelligence (AI) that enables decentralised diagnostics and personalised treatment. According to […]

Twist Bioscience has reported that its internally-discovered antibody candidate TB202-3 (CoVIC-094) demonstrated potent binding to diverse SARS-CoV-2 variant mutations, including strains with the E484K, N501Y, D614G, Y453F and K417N mutations in pseudovirus assays, indicating this therapeutic antibody may be effective in treating many strains of Covid-19.   The Coronavirus Immunotherapy Consortium (CoVIC), an academic-industry, non-profit collaborative research effort, […]

In this video, Dr Gary Allenby, CEO Aurelia Bioscience, describes a scientific poster on ‘Magnetic Electrospun Micro-fibre Scaffold Assemblies: Examples of their use for 3-Dimensional Cell-Based Screening Applications’. How the technology works: Aurelia Bioscience has developed a 3-D micro-tissue system from electrospun material that can be used in conjunction with well plates for higher throughput […]

GSK has announced that it planning to develop its research & development site in Stevenage, UK,  into one of Europe’s largest clusters for biotechnology and early-stage life science companies. The concept has been developed in partnership with Stevenage Bioscience Catalyst (SBC), among others and would build on GSK’s existing presence, the Cell and Gene Therapy […]

Listen to this article on the DDW Podcast:   To understand Switzerland’s continued success in the biotech sector and gain personal insights, Lu Rahman spoke to Michael Altorfer (CEO of the Swiss Biotech Association), Jan Lucht (Head of Biotechnology, scienceindustries), Claude Joris (Secretary General, BioAlps), and Carole Delauney (Business Development Director at swissfillon). With a population […]

Aurelia Bioscience, a Nottingham, UK based pre-clinical Contract Research Organisation (CRO) has produced a new video to explain the functioning of WES and JESS – two highly reproducible, capillary based, automated western blot instruments from ProteinSimple: Whilst traditional western blotting typically runs 10-20 samples in three to five hours and requires 24-48 hours to produce […]

Taconic Biosciences has launched a new solution, TruIMPORT, for importing genetically engineered models from China into academia vivarium without quarantine, in collaboration with Cyagen. Researchers at non-profit institutions play a critical role in drug discovery; however, outsourcing animal model generation can be cost prohibitive or a logistical challenge. Hurdles in accessing animal model resources can […]

Using Promega’s NanoBRET technology, scientists at Aurelia Bioscience have implemented intracellular kinase assays designed to study the interaction of compounds on kinase targets in intact living cells. Advantages of this technique include examination of compound binding to target kinases at physiological ATP concentrations, expression of full-length kinase target in cells, disruption of cells (with digitonin) […]

The Cell & Gene Collective has been launched by companies Astellas, bluebird bio, Bristol Myers Squibb, Kite (a Gilead company) and Novartis with the aim of raising awareness of the promise and challenges of the next generation of medicines – cell and gene therapies. To date, the UK has introduced a number of cell and […]

Charles River has signed a definitive agreement to acquire Vigene Biosciences. The purchase price is expected to be US$292.5 million, subject to customary closing adjustments. The acquisition will enhance Charles River’s gene therapy capabilities in the high-growth, value-added cell and gene therapy CDMO sector. In addition to the initial purchase price, the transaction includes contingent […]

Pelago Bioscience is a specialised CRO, focusing on its patented Cellular Thermal Shift Assay (CETSA), which can assess therapeutically relevant target engagement in cells or tissue of unmodified compounds against the native, full-length proteins of interest. Stina Lundgren, Principal Project Advisor, shared the company’s hit-to-lead expertise with Lu Rahman. CETSA by Pelago can be adapted […]

Taconic Biosciences, providers of animal model solutions for drug discovery, has launched a new Covid-19 mouse model. This human ACE2 (hACE2) transgenic mouse expands Taconic’s Covid-19 research toolkit. In October 2020, Taconic launched its first hACE2 model. The AC70 mouse experiences a lethal response to infection by SARS-CoV-2, the virus that causes Covid-19. Conversely, the […]

Aurelia Bioscience is a pre-clinical contract research organisation specialising in bioassay development, pharmacological profiling and compound screening. Scientists at Aurelia Bioscience have experience developing new and innovative bio-assays for different target classes using technologies to deliver client projects in a timely, efficient and cost-effective manner. Using Promega’s NanoBRET technology, Aurelia Bioscience has implemented intracellular kinase […]