Aptamers

#Aptamer Group #Aptamers #Biomarkers #Drug discovery

Aptamer launches biomarker discovery service

Aptamer Group has launched its biomarker discovery service, offering researchers in pharmaceutical, biotechnology, and diagnostic development a new approach to identify and validate new disease markers.  The service integrates Aptamer’s Optimer technology with proteomic analysis to provide an unbiased, high-throughput approach to biomarker identification.   This… Read More

#News

siRNA
#Aptamer Group #Aptamers #AstraZeneca #Collaboration #Gene therapy #siRNA

AstraZeneca and Aptamer test liver delivery vehicles with siRNA

Aptamer Group and AstraZeneca have entered a collaboration agreement to evaluate Aptamer’s Optimer fibrotic liver delivery vehicles for the targeted delivery of small interfering RNA (siRNA). Following the encouraging results achieved to-date with Aptamer’s fibrotic liver delivery vehicles, the next phase of the research will… Read More

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#Aptamer Group #Aptamers #Automation #Drug delivery #Gene delivery #Gene therapy #Molecular Biology #Oncology #Precision medicine #Turning Science into Business

Turning science into business: An optimised alternative to antibodies

From humble beginnings in the founder’s basement, UK-based Aptamer Group is now supplying its Optimer binders to clients across big pharma. DDW’s Diana Spencer caught up with co-founder and CEO Dr Arron Tolley. DS: What motivated you and Dr David Bunka, CTO, to create Aptamer and did… Read More

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Blocked artery
#Aptamers #Basking Biosciences #ischaemic stroke #Phase I trial #RNA

RNA aptamer reopens blocked arteries

Biopharmaceutical company Basking Biosciences has revealed positive Phase I study results for its reversible thrombolytic therapeutic for ischaemic stroke.  The company’s novel von Willebrand Factor (vWF)-targeting thrombolytic agent, BB-031 demonstrated safety and tolerability following a single intravenous dose.   The study results were presented at the… Read More

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#Aptamers #CAR-T #Immunotherapy #Oncology

Research collaboration will develop bispecific agents for oncology

Ixaka and SomaLogic have created a research collaboration to support the development of aptamer-based bispecific therapeutics. The collaboration will evaluate the safety and efficacy of antigen-specific SOMAmer reagents (modified aptamers that bind tightly and specifically to protein targets) previously identified and screened by SomaLogic as potential candidates for combination with… Read More

#Cancer Research #News