Antimicrobials

Ineos, one of the world’s largest manufacturing companies, and the University of Oxford are launching a new world-leading institute to combat the growing global issue of antimicrobial resistance (AMR), which currently causes an estimated 1.5 million excess deaths each year- and could cause over 10m deaths per year by 2050. Predicted to also create a […]

Antibiotics & Antimicrobial Resistance (AMR) – A Global Perspective Professor Anthony Coates and Dr Yanmin Hu Antibiotic resistance is at a crossroad. In the world today, deaths in low income countries from Antimicrobial Resistance (AMR) are predicted to rise dramatically by 2050. We know how to stop this disaster, and some steps are being taken […]

The Human Microbiome – A new frontier in drug discovery By Lee Jones There is a new phenomenon sweeping the globe (or at least sweeping the imagination of people around the globe). It is the human gut microbiome and the role it may play in the future of human health. Recent reports have indicated that […]

Anti-Infective Immunotherapy For Treating Hospital Acquired Infections By Dr Vu Truong, Dr Nadine Weich, Dr Andreas Loos and Dr Eric Patzer The frequency of nosocomial (acquired in healthcare facility) pneumonia has experienced a steady increase in recent years, and treatment of these infections has become more challenging and expensive due to the emergence of multi-drug […]

Exploring The Feasibility of Human Antimicrobial Peptides For New and More Efficient Antibiotics By Dr Max Ryadnov To help combat decades of stagnation in antibiotic development, a team led by the National Physical Laboratory conducted two studies into the antimicrobial peptides that fight infection in our bodies and the feasibility of using them as the […]

Meeting the challenge of healthcare-associated infections with new antimicrobials: with a focus on Clostridium difficile By Professor Peter Hawkey and Dr Katie Hardy Healthcare-associated infections (HCAI), previously known as hospital acquired infections (HAI), are defined as infections resulting from medical care or treatment in hospital. HCAI may be caused by any infectious agent from endogenous […]

Plants as a source of new medicines By Jennie Gwynn and Peter J Hylands Putting aside the excitement surrounding the human genome, in the near future we may well start to see the emergence of a new class of prescription medicine containing complex mixtures of plant extracts. This article discusses the important role that plants […]