During early development of biologics, there are a large number of attributes researchers evaluate, but some of the most common centre around stability – asking if a biologic is well-folded, active and pure in its buffer, and whether it remains that way over time. Biophysical characterisations are valuable for providing this information without using a lot of material.
Read more to learn about technologies for characterisation of your candidates during biologic development.
You’ll learn about:
- The different stages at which biophysical characterisation is necessary for early biologic development
- Which biophysical parameters are needed to make decisions to the next stage
- How measurements from nanoDSF, DLS, backreflection, and SLS support each of those steps from target selection to IND
