Selective degradation of cancer target WDR5 — Evaluation of PROTACs binary and ternary affinities with Spectral Shift

Watch On Demand

As more and more R&D pipelines include PROTAC candidates — the race to bring successful and efficient protein degraders to the clinic is on. These targets present challenges in the biophysical characterisation of binary and ternary complexes, making developing effective degraders complicated.

Watch this on-demand webinar to learn:

  • How Spectral Shift technology lets you take measurements in-solution and immobilisation free
  • What the data from a Spectral Shift experiment characterising protein degraders looks like
  • How to save time and sample by reducing the need for complex assay development when working with binary and ternary interactions

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