Plant-based squalene alternative suitable for vaccine use

Amaranth oil

Evonik has launched a non-animal-derived squalene suitable for vaccines and other pharmaceutical applications.

PhytoSquene is the first known amaranth oil-derived squalene on the market for use in adjuvants in parenteral dosage forms. It is an alternative to animal-derived squalene, which for pharmaceutical applications is typically sourced from shark liver oil. 

“It is alarming that biodiversity across our planet is declining at a rapid rate. That’s why we are excited about empowering our customers to create products that preserve biodiversity and, at the same time, deliver high-quality treatments to patients,” said Thomas Riermeier, Head of the Health Care business line at Evonik. 

PhytoSquene is made from the oil of amaranth (Amaranthus caudatus) which is an herbaceous plant cultivated in many parts of the world. 

Squalene is a natural organic compound that is used as a component in some adjuvant systems. Adjuvants are additives that boost the body’s immune response to the active ingredient in a vaccine. They reduce the amount of active ingredient needed, thus making it faster and easier to scale vaccine production, and reducing the chance of any side effects in patients. 

This new product follows the launch, earlier this year, of plant-derived cholesterol PhytoChol.

Related Articles

Join FREE today and become a member
of Drug Discovery World

Membership includes:

  • Full access to the website including free and gated premium content in news, articles, business, regulatory, cancer research, intelligence and more.
  • Unlimited App access: current and archived digital issues of DDW magazine with search functionality, special in App only content and links to the latest industry news and information.
  • Weekly e-newsletter, a round-up of the most interesting and pertinent industry news and developments.
  • Whitepapers, eBooks and information from trusted third parties.
Join For Free