Mouse models with human immune cell engraftment provide platforms to evaluate compounds to treat a variety of human diseases.
Humanised PBMC (hu-PBMC) mice feature quick engraftment of adult peripheral blood mononuclear cells and enable short-term studies requiring mature human T cells. Hu-PBMC mice are used as in vivo models to study and evaluate compounds for T cell immune modulation, infectious diseases and graft rejection research.
Download the new whitepaper from The Jackson Laboratory to learn about:
- The benefits of the JAX NSG-MHC I/II KO mouse platform humanised with pre-characterised peripheral blood mononuclear cells (PBMCs)
- How this platform can support a wide range of immunological studies, especially those containing T cells responses
- The versatility of this platform to various research disciplines