Whitepaper: The benefits of a mouse platform humanised with PBMCs

Lab mouse
14 September 2022
Posted in News | Tagged , ,

Mouse models with human immune cell engraftment provide platforms to evaluate compounds to treat a variety of human diseases.

Humanised PBMC (hu-PBMC) mice feature quick engraftment of adult peripheral blood mononuclear cells and enable short-term studies requiring mature human T cells. Hu-PBMC mice are used as in vivo models to study and evaluate compounds for T cell immune modulation, infectious diseases and graft rejection research.

Download the new whitepaper from The Jackson Laboratory to learn about:

  • The benefits of the JAX NSG-MHC I/II KO mouse platform humanised with pre-characterised peripheral blood mononuclear cells (PBMCs)
  • How this platform can support a wide range of immunological studies, especially those containing T cells responses
  • The versatility of this platform to various research disciplines

Download here.

Suggested Reading

Mice with humanised immune systems advance cell-based immunotherapy
22 July 2022

Join FREE today and become a member
of Drug Discovery World

Membership includes:

  • Full access to the website including free and gated premium content in news, articles, business, regulatory, cancer research, intelligence and more.
  • Unlimited App access: current and archived digital issues of DDW magazine with search functionality, special in App only content and links to the latest industry news and information.
  • Weekly e-newsletter, a round-up of the most interesting and pertinent industry news and developments.
  • Whitepapers, eBooks and information from trusted third parties.
Join For Free