Whitepaper: The benefits of a mouse platform humanised with PBMCs

Lab mouse
14 September 2022
Posted in News | Tagged , ,

Mouse models with human immune cell engraftment provide platforms to evaluate compounds to treat a variety of human diseases.

Humanised PBMC (hu-PBMC) mice feature quick engraftment of adult peripheral blood mononuclear cells and enable short-term studies requiring mature human T cells. Hu-PBMC mice are used as in vivo models to study and evaluate compounds for T cell immune modulation, infectious diseases and graft rejection research.

Download the new whitepaper from The Jackson Laboratory to learn about:

  • The benefits of the JAX NSG-MHC I/II KO mouse platform humanised with pre-characterised peripheral blood mononuclear cells (PBMCs)
  • How this platform can support a wide range of immunological studies, especially those containing T cells responses
  • The versatility of this platform to various research disciplines

Download here.

Suggested Reading

Mice with humanised immune systems advance cell-based immunotherapy
22 July 2022
The evolving immuno-oncology landscape 
5 January 2022

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