Author Archives: Megan Thomas

#Biotechnology #Cardiometabolic diseases #Drug development #Drug discovery #ICON #Pharmaceuticals #Survey

More efficient next-gen obesity clinical trials needed, says survey

ICON has released the findings of a survey of 155 biotech and pharma professionals from across the US and Europe, focusing on multi-indication cardiometabolic R&D for therapies targeting obesity and its comorbidities. Multi-indication studies are clinical trials that test how a treatment works for more than one condition or disease. Read More

#News

#DDW Highlights podcast #European Commission #FDA #Regulatory

New DDW Highlights podcast: 19 May 2025

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. Our news highlights this time focus on two major regulatory agencies, in a week… Read More

#News

#DDW Highlights podcast

DDW Highlights: 19 May 2025

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. Our news highlights this time focus on two major regulatory agencies, in a week… Read More

#Podcasts

Neurons in the brain
#Alta Neuroscience #Alzheimer's #Biomarkers #Blood-based biomarkers #Diagnostics #Roche

How Roche is advancing Alzheimer’s research

DDW’s Megan Thomas speaks with Dr Maria-Magdalena Patru, Scientific Partner at Roche Diagnostics US, about how advances in Alzheimer’s disease (AD), particularly blood-based biomarkers (BBM), can enable earlier, more accurate, and accessible detection of the disease, supporting timely treatment and improved patient outcomes.  MT: Why is improving AD diagnostics crucial… Read More

#Exclusive Content

#AI / data analytics / healthtech / informatics #Cancer research #Drug discovery #Emulate #Gene expression #Gene therapy #Interview #Metabolomics #Multi-omics #Next generation sequencing #NGS #Omics #Organ-on-a-chip #Personalised medicine #Preclinical investigations #Spatial biology

Podcast: Cutting-edge tools shaping early-stage drug discovery

This is the latest episode of the free DDW narrated podcast, titled “Cutting-edge tools shaping early-stage drug discovery”, which covers three articles written for DDW Volume 24 – Issue 4, Fall 2023. They are called: “The use-case for NGS”, “Are organ-chips the future of preclinical… Read More

#News

#Narrated podcasts

Cutting-edge tools shaping early-stage drug discovery

This is the latest episode of the free DDW narrated podcast, titled “Cutting-edge tools shaping early-stage drug discovery”, which covers three articles written for DDW Volume 24 – Issue 4, Fall 2023. They are called: “The use-case for NGS”, “Are organ-chips the future of preclinical… Read More

#Podcasts

Approval stamp
#Drug approvals #Fragile X Syndrome #Kaerus Bioscience #Regulatory

Approvals granted for the treatment of Fragile X Syndrome 

Kaerus Bioscience’s lead candidate KER-0193 has been granted both Orphan Drug Designation and Rare Pediatric Drug Designations for the treatment of Fragile X syndrome (FXS) by the US Food and Drugs Administration (FDA). This follows the recent successful completion of a Phase I trial of KER-0193 in healthy volunteers, which… Read More

#News #Regulatory

Cancer research
#AACR #AACR 2025 #Cancer research #Opinion

Expert reflections from AACR 2025

DDW’s Megan Thomas hears from industry experts Daniel Veres, Turbine’s Chief Scientific Officer & Co-Founder, as well as Ryan Jacobs, Business Development Manager at Astoriom, about AACR 2025. MT: What do you consider to be the key trends in cancer research? Daniel Veres: Key trends in cancer research include a… Read More

#Cancer Research #Exclusive Content #Opinion

CAR-T cells attacking a cancer cell
#Cancer research #CAR-T #Cell and gene therapy #Leucid Bio #Solid tumours

First patient dosed in CAR-T therapy trial for solid tumours

Leucid Bio has dosed the first patient in the Phase I AERIAL trial evaluating the safety and clinical activity of LEU011 in patients with refractory solid tumours. Initiation of the AERIAL trial follows the successful first close of the Series A1 financing of £7.2 ($9.51) million in February 2025, co-led… Read More

#Cancer Research #News

#Cancer research #Oncology #Solid tumours

New DDW Highlights podcast: 12 May 2025

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. Our highlights this week demonstrate a variety of approaches to cancer treatment, including a… Read More

#News

#DDW Highlights podcast

DDW Highlights: 12 May 2025

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. Our highlights this week demonstrate a variety of approaches to cancer treatment, including a… Read More

#Podcasts

Antibody drug conjugate
#Antibody drug conjugate (ADC) #Bispecific Antibodies #Cancer research #Solid tumours #SOTIO

The challenges in solid tumour targeting with bispecific ADCs

Czech biotechnology company, SOTIO, recently started preclinical development of its first two bispecific antibody drug conjugates (ADCs), which it says are “just the beginning” of what it has in store for its next-generation ADC pipeline. DDW’s Megan Thomas speaks with SOTIO’s Chief Scientific Officer, Martin Steegmaier, about the company’s pipeline. Read More

#Cancer Research #Exclusive Content

Double stranded DNA molecule with mutation in a gene
#In Conversation Series

The next generation of respiratory therapeutics

In the In Conversation With series, a part of the free DDW podcast, DDW speaks with members of the drug discovery industry about their work and how it helps turn science into business.    In this episode, Megan Thomas is in conversation with Dimitrios Goundis, CEO… Read More

#Podcasts

Double stranded DNA molecule with mutation in a gene
#Clinical trials #Cystic fibrosis #Drug delivery #Drug development #Europe #Kither Biotech

In Conversation With: Dimitrios Goundis, Kither Biotech

In the In Conversation With series, a part of the free DDW podcast, DDW speaks with members of the drug discovery industry about their work and how it helps turn science into business.    In this episode, Megan Thomas is in conversation with Dimitrios Goundis, CEO… Read More

#News

Human adenovirus
#biological engineering #CAR-T #Cell and gene therapy #Cell therapy #EsoBiotec #In vivo

Revolutionising cancer treatment with viral vectors

CAR-T cell therapy has revolutionised cancer treatment, offering life-changing outcomes for patients with haematological malignancies. Jean-Pierre Latere, PhD, CEO of EsoBiotec, discusses advances in in vivo engineering, which are poised to overcome manufacturing and cost barriers, making these therapies more accessible and expanding their potential applications. The landscape of cancer… Read More

#Cancer Research #Exclusive Content

#AACR #AACR 2025 #Cancer research #Oncology

New DDW Highlights podcast: 7 May 2025

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. With the American Association of Cancer Research (AACR) Annual Meeting taking place from 25-30 April,… Read More

#News