Webinar: Obtaining quality data from biosensors

Tips and tricks on how to obtain and analyse high quality data from live cell, high throughput assays of signalling dynamics.

Genetically encoded fluorescent biosensors enable continuous recording of cellular signaling in live cells. This breakthrough technology provides unprecedented, real-time measurements of signaling dynamics, which is emerging as a critical determinant of physiological function and therapeutic targeting of signaling proteins.

In this webinar Agilent BioTek will go through the scientific and technological tips and tricks to obtain high quality, high throughput kinetic data on BioTek plate readers, with biosensors for G-protein-coupled receptor second messengers and arrestin recruitment. We will then describe how to analyse signalling dynamics by applying curve fitting to the time course data. This analysis is straightforward, and we provide a plug-in for the curve-fitting programme GraphPad Prism to enable analysis with familiar software. This reveals new insights exemplified by differential signalling kinetics and arrestin recruitment mechanisms for multiple GPCRs.

Date: Wednesday, August 31, 2022

Time: 12:00 PM Eastern Daylight Time

Duration: 1 hour

Key Learning Objectives:

  • Technological tips and tricks to obtain high quality, high throughput kinetic data on BioTek plate readers
  • How to analyse signalling dynamics by applying curve fitting to the time course data

Register here

Related Articles

Join FREE today and become a member
of Drug Discovery World

Membership includes:

  • Full access to the website including free and gated premium content in news, articles, business, regulatory, cancer research, intelligence and more.
  • Unlimited App access: current and archived digital issues of DDW magazine with search functionality, special in App only content and links to the latest industry news and information.
  • Weekly e-newsletter, a round-up of the most interesting and pertinent industry news and developments.
  • Whitepapers, eBooks and information from trusted third parties.
Join For Free