Genetic medicines company nChroma Bio has received a Certificate for Clinical Trial in Hong Kong to start the Phase I/II trial of its treatment for chronic hepatitis B virus (HBV). CRMA-1001 is an optimised next-generation epigenetic silencer, designed to durably silence HBV antigen expression by methylating both covalently closed circular… Read More
Bluejay Therapeutics’ AZURE-1 global pivotal clinical trial evaluating brelovitug (BJT-778) for the treatment of chronic hepatitis D (CHD) has dosed its first patient. Brelovitug is an investigational fully human immunoglobulin G1 (IgG1) monoclonal antibody (mAb) that targets the surface antigen (anti-HBsAg) on both the hepatitis D virus… Read More
Epigenome editing company Tune Therapeutics has showcased new data at the American Association for the Study of Liver Diseases (AASLD) conference, in support of its drive to develop a lasting, functional cure for chronic Hepatitis B Virus (HBV). Tune presented its lead HBV programme at the 2023 iteration of the… Read More
SCG Cell Therapy has announced late-breaking data from its Phase I trial of SCG101, a first-in-class autologous hepatitis B virus (HBV)-specific T-cell receptor-engineered T cell (TCR-T) therapy targeting hepatitis B surface antigen (HBsAg). The data was presented at the 2024 AASLD Liver Meeting in San Diego, United… Read More
A new study from Korea University suggests that treatment with direct-acting antivirals (DAAs) improves liver disease-related clinical outcomes in patients with chronic hepatitis C virus (HCV) infection and reduces liver fibrosis-based disease burden. In recent years, DAAs that block replication of HCV have dramatically transformed the… Read More
Roche Diagnostics and ABL Diagnostics have launched a distribution partnership which will see Roche supplying ABLD products to South African laboratories. Roche now has exclusive rights to distribute products, including the ABL DeepChek assays to laboratories implementing microbiology applications. These applications include HIV, Tuberculosis, Cytomegalovirus, Viral… Read More
