Verve Therapeutics

Gene editing
#Eli Lilly #Gene editing #Gene therapy #Mergers and acquisitions #Verve Therapeutics

Lilly to acquire gene editing specialists Verve Therapeutics

Eli Lilly and Verve Therapeutics have announced a definitive agreement for Lilly to acquire Verve.  Verve is developing a pipeline of gene editing medicines designed to address the drivers of atherosclerotic cardiovascular disease (ASCVD) through treatments that may only need to be given once in a lifetime.   Verve's lead programme… Read More

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Gene therapy
#Cardiovascular disease #Gene editing #Genetics / genomics #In vivo #Verve Therapeutics

Single-course in vivo base editing therapy proven to lower cholesterol

A Phase Ib trial has shown low-density lipoprotein cholesterol (LDL-C) reductions up to 55% and blood PCSK9 protein reductions up to 84% after a single infusion of Verve Therapeutics’ Verve-101. The trial participants have heterozygous familial hypercholesterolemia (HeFH), a life-threatening inherited disease characterised by lifelong elevations… Read More

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