The latest episode of the DDW Highlights Podcast is now available to listen to below. DDW’s Bruno Quinney narrates five key stories of the previous week to keep DDW subscribers up-to-date on the latest industry news. Last week’s discoveries into Parkinson’s disease, allergies and common cancers could shape drug development. Elsewhere,… Read More
News round-up for 26 – 30 January by Bruno Quinney, Content Team at DDW. This week in DDW, discoveries into Parkinson’s disease, allergies and common cancers could shape drug development. Elsewhere, why is the UK leading Europe’s biotech market? The top stories: Parkinson’s could be identified in… Read More
A new study has revealed that low levels of CTDNEP1 may drive early and deadly pancreatic tumours, highlighting its role as a tumour suppressor. Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer and begins in the cells lining the pancreatic duct. Accounting for… Read More
Researchers at Tokyo University of Science have successfully developed a new method to synthesise eutyscoparol A and violaceoid C, two naturally occurring compounds with promising antimalarial and antibacterial properties. The new approach involves the synthesis of these compounds using readily available dinitriles. This method requires fewer… Read More
Researchers in Japan have revealed why geometric variants of doxepin have markedly different efficacies, paving the way to next-generation antihistamines with fewer side effects. Doxepin is an antihistaminic, antidepressant, and sleeping aid that has two geometric isomers – molecules with equal chemical formulas but different 3D… Read More
Researchers have identified a novel target downstream of parathyroid hormone (PTH) signalling that suppresses bone formation in osteoporosis. The PTH-derived peptide teriparatide has demonstrated strong bone promoting effects. However, it is also to known to exert bone-resorbing effects. A new study uncovers a novel… Read More
Researchers have discovered that nanoparticles derived from rice bran are both effective and safe for the treatment of cancer. Cancer therapies that employ nanoparticles can specifically target cancer cells, sparing healthy tissue. Recent studies have demonstrated that plant-derived nanoparticles (pdNPs) that have therapeutic effects… Read More
A new study has highlighted the role of specific neuronal circuits in the brain involved in the development of anxiety, and distinct mechanisms of action of the therapeutic delta opioid receptor (DOP) agonist KNT-127. Understanding the neural circuits and molecular mechanisms that trigger anxiety can aid… Read More
Researchers from Tokyo University of Science (TUS) have found a simple, low-cost way to optimise the production of monoclonal antibodies (mAbs) and reduce manufacturing costs. Dr Kyohei Higashi, Associate Professor at TUS, along with a team of researchers, conducted a study to explore the effects of… Read More
Scientists from Tokyo University of Science have shed light on how various molecules are recruited in endocytosis, a cellular process of bringing in different types of materials from the outside. The results suggest key regulatory functions of the yeast Eps15-like protein Pan1p. The findings provide important insights into the process,… Read More
