Pneumonia

Testing antiviral vaccines in the lab
#Antivirals #Covid-19 treatment #Ebola virus #Infectious diseases #Pneumonia #University of Queensland #Viral infections #Virus treatment

The lightbulb moment behind a potential antiviral breakthrough 

An unexpected observation by a University of Queensland (UQ) researcher could lead to a new treatment for deadly infectious diseases including Covid‑19, pneumonia in infants and children, or viral infections caused by Ebola and hantavirus.   UQ’s Australian Institute for Bioengineering and Nanotechnology neuroscientist and biochemist Dr… Read More

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Patient on ventilator
#Covid-19 #Covid-19 treatment #Drug repurposing #Francis Crick Institute #Pneumonia #University College London

Repurposed drug treats severe Covid-19 pneumonia

A drug commonly used to treat cystic fibrosis improved outcomes for patients with severe Covid-19 pneumonia in a recent clinical trial. The drug, dornase alfa, could be used to treat other respiratory infections, according to the data from researchers at UCL, UCLH and the Francis Crick… Read More

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Doctor vaccinating baby
#FDA #Immunology / Virology & Vaccines #Paediatric #Phase II trial #Pneumonia

Pneumococcal vaccine gets go-ahead for infant trial

The US Food and Drug Administration (FDA) has cleared Vaxcyte’s infant Investigational New Drug (IND) application for VAX-24, its 24-valent pneumococcal conjugate vaccine (PCV) candidate designed to prevent invasive pneumococcal disease (IPD).  The company plans to initiate the infant Phase II study in the second… Read More

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Pneumococcal disease vaccine
#Clinical trial #FDA #Immunology / Virology & Vaccines #Pneumonia #Regulatory #United States #Vaxcyte

Breakthrough Therapy designation for pneumococcal disease vaccine

The US Food and Drug Administration (FDA) has granted Breakthrough Therapy designation for VAX-24, Vaxcyte’s 24-valent pneumococcal conjugate vaccine for the prevention of invasive pneumococcal disease.  The decision was based on positive topline results from a Phase I/II proof-of-concept study, which evaluated the safety, tolerability… Read More

#News #Regulatory

#Biomarkers #Clinical trials #Covid-19 #Pharma #Pneumonia #Research

Ruconest-treated patients test lower disease severity scores for Covid-19 

Pharming Group has announced the topline results from two randomised, open label, controlled, pilot clinical trials of patients hospitalised with Covid-19 treated with Ruconest (recombinant human C1 inhibitor) for the prevention of severe SARS-CoV-2 infection. The primary endpoint in both studies was disease severity on the seven-point WHO ordinal scale on Day Seven. … Read More

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#Clinical specialities #Covid-19 #Pneumonia

Campaign and conference shine light on importance of pneumonia research

The PneumoLight campaign, in collaboration with Pfizer – and coinciding with World Pneumonia Day – will see 232 buildings and monuments from 48 different countries will be illuminated in blue. The project involves Dr. Catia Cilloniz, a researcher at the Hospital Clínic of Barcelona, the University of Barcelona (UB), the Barcelona… Read More

#Covid-19 #News