Muscles

Researchers have identified the genetic links between muscle atrophy and two types of myosin, paving the way for a new disease model for scientific research and potential new treatments.  The synergistic action of the muscle proteins myosin and actin enables skeletal muscle movements. The skeletal muscle myosin heavy chain or “MyHC” is a fundamental component […]

BridgeBio has been granted Fast Track designation United States Food and Drug Administration (FDA) for the investigation of BBP-418 as a treatment option for Limb-girdle Muscular Dystrophy Type 2i (LGMD2i). This is the fifth Fast Track designation for an investigational therapy that BridgeBio has received in 2021.  BridgeBio’s LGMD2i investigational therapy is one of the company’s 14 programs that […]

Scientists at St. Jude Children’s Research Hospital are studying how signals sent from skeletal muscle affect the brain. The team studied fruit flies and brain cell models called organoids, focusing on the signals that muscles send when stressed. They used immunostaining and confocal microscopy on the fruit fly brain and found that stress signals rely […]