New research has revealed that structurally novel neurokinin-1 receptor (NK1R) inhibitors reduce depressive-like behaviour and brain inflammation in mice. For decades, scientists have investigated the NK1R as a potential target for treating major depressive disorder. Early studies suggested promise, but enthusiasm faded after clinical trials of drugs… Read More
A new study from Korea University suggests that treatment with direct-acting antivirals (DAAs) improves liver disease-related clinical outcomes in patients with chronic hepatitis C virus (HCV) infection and reduces liver fibrosis-based disease burden. In recent years, DAAs that block replication of HCV have dramatically transformed the… Read More
Korean scientists have found that HVH-2930, an innovative HSP90 inhibitor, demonstrates promising efficacy in inducing cancer cell apoptosis and overcoming treatment resistance in HER2-positive breast cancer. Unlike previous HSP90 inhibitors, the compound circumvents limitations by bypassing heat shock response (HSR) induction. Professor Jae Hong… Read More
