Imaging

#3D deep learning imaging #Deep learning #Drug discovery #Financing #Imaging #Qureight #Series B financing

Qureight closes $20 million Series B financing 

Cambridge data analytics company Qureight has raised $20 million in a Series B financing, led by Molten Ventures, which will support expansion of the Company’s 3D deep learning imaging portfolio, alongside commercial expansion to address demand across key new therapeutic markets for lung and heart diseases.  Existing investors Hargreave Hale… Read More

#News

TARGA imager
#App note #Imaging #Neurodevelopmental disorders #Neuroscience

App Note: Neurodevelopmental disease revealed with TARGA Imager

The study of neurodevelopmental diseases such as schizophrenia requires imaging tools capable of capturing complex neuronal behaviour at scale. This Application Note identifies Lumencor’s TARGA Imager enabling high-speed calcium imaging using NGN2 neurons and stem cell–derived neuronal models to study collective cellular dynamics with exceptional spatial and temporal resolution. Read More

#News

Fibrosis lungs
#3D imaging #Artificial intelligence (AI) #Calluna Pharma #Idiopathic pulmonary fibrosis #Imaging #Phase II trial #Qureight

AI 3D imaging platform supports Calluna’s IPF trial

Calluna Pharma will use Qureight’s AI-powered imaging and clinical data curation platform to support its Phase II AURORA study.   Qureight will analyse imaging data from adult patients, evaluating anatomical lung changes in individuals treated with CAL101, Calluna’s lead asset for the treatment of idiopathic pulmonary fibrosis (IPF). Read More

#News

#Cell analysis #Drug discovery #Guide #Imaging #Spatial biology

Accelerate your imaging research with the updated protocols guide

The second edition of the ‘Imaging protocol handbook‘ from Thermo Fisher Scientific is now available to download for free. This handbook will help you accelerate your research by helping you plan and execute your imaging experiments. The Guide covers main procedural steps to achieve your best results. Plan and… Read More

#News

#Cell analysis #Drug discovery #Imaging #Spatial biology

Imaging protocol handbook

This imaging protocol handbook will help you accelerate your research by helping you plan and execute your imaging experiments. The Guide covers main procedural steps to achieve your best results. Plan and optimise imaging experiments with clear, step-by-step procedural guidance. Master core and advanced techniques—from cell proliferation and immunolabeling to… Read More

#Resources

#Assays #Drug discovery #Imaging #Live cell analysis #Macrophages #Phenotyping #Technical Note

Optimise macrophage assays and boost immunology research

A new free resource from Lonza is now available entitled ‘Optimising macrophage polarisation and phagocytosis assays‘. Download this Technical Note to learn: Streamlined Macrophage Workflow: Transform cryopreserved or PBMC-derived monocytes into M1 or M2 macrophages using a reproducible, high-throughput protocol. Comprehensive Validation: Confirm phenotype and function with live-cell imaging… Read More

#News

#Assays #Drug discovery #Imaging #Live cell analysis #Macrophages #Phenotyping

Optimising macrophage polarisation and phagocytosis assays

Download this Technical Note to learn: Streamlined Macrophage Workflow: Transform cryopreserved or PBMC-derived monocytes into M1 or M2 macrophages using a reproducible, high-throughput protocol. Comprehensive Validation: Confirm phenotype and function with live-cell imaging and phagocytosis assays for application-ready results. Accelerated Research: Enhance drug discovery, immunotoxicology, and screening workflows with both… Read More

#Resources

#App note #Artificial intelligence (AI) #Drug discovery #Imaging

App Note: Your AI-enhanced solution for viral infectivity analysis

Discover how the Agilent BioTek Cytation cell imaging multimode reader and ViQi’s AVIA provide a powerful, integrated solution for viral infectivity analysis. Download the Application Note to explore how this innovative approach offers key advantages over traditional assays, including: High-throughput, cost-effective analysis: AVIA minimises reagent use, incubation time, and replicate… Read More

#News

#Imaging #Microscopy #Molecular Biology #New York University

Biomolecular condensates finding could shape drug development

A team of New York University (NYU) chemists and physicists have unlocked how cells build and grow tiny, dynamic droplets known as biomolecular condensates.  For the first time, scientists measured the protein content and growth dynamics of individual biomolecular condensates without disturbing them, gaining insights that may… Read More

#News

#App note #Artificial intelligence (AI) #Drug discovery #Imaging

Your AI-enhanced solution for viral infectivity analysis

Discover how the Agilent BioTek Cytation cell imaging multimode reader and ViQi’s AVIA provide a powerful, integrated solution for viral infectivity analysis. Download the application note to explore how this innovative approach offers key advantages over traditional assays, including: High-throughput, cost-effective analysis: AVIA minimises reagent use, incubation time, and replicate needs,… Read More

#Resources

#Alzheimer's #Cellular imaging #Drug discovery #Imaging #Japan #Nanobodies #Neuroscience

Nanobody-based 3D imaging boosts neuroscience research

Scientists have created a nanobody-based method that enables ultra-fast, high-resolution 3D mapping of neurons and glia in thick brain tissues.  The researchers from Japan have developed a fast, high-sensitivity three dimensional immunohistochemistry (3D-IHC) method using nanobodies fused with peroxidase and a novel signal amplification system.  … Read More

#News

#Artificial intelligence (AI) #Drug discovery #eBook #Imaging

eBook: The importance of imaging in drug discovery

Various imaging modalities are used throughout the process of drug discovery and development, both in the preclinical and clinical phases. According to analysts, Valuates, the global preclinical imaging market was valued at $1887.9 million in 2023 and is anticipated to reach $3021.2 million by 2030. Read More

#News

DDW Imaging eBook
#Artificial intelligence (AI) #Drug discovery #eBook #Imaging

The importance of imaging in drug discovery

This eBook, sponsored by Aurora Microplates, examines the role of imaging and its significance to the success of drug discovery and development. Download this exclusive eBook to learn more about: Two technological developments that have revolutionised the role of imaging in drug discovery The latest innovations in flow cytometry technology… Read More

#DDW eBooks #Intelligence

#Deep learning #Idiopathic pulmonary fibrosis #Imaging #Phase II trial #Qureight

Deep-learning imaging technology to enhance Phase II trial

Biopharmaceutical company Rein Therapeutics and core imaging laboratory Qureight have announced plans to collaborate on an idiopathic pulmonary fibrosis (IPF) clinical trial.  The companies will integrate Qureight’s deep-learning platform into Rein’s planned Phase II trial of its lead asset LTI-03, a novel, multi-pathway, Caveolin-1-related peptide.  … Read More

#News

#Artificial intelligence (AI) #Clinical trial design #Deep learning #Fibrosis #Imaging #Interview

How is deep learning imaging advancing drug discovery for fibrosis?

Diana Spencer speaks to Dr Muhunthan Thillai, CEO at Qureight, about the company’s AI-powered imaging analytics and the technology’s potential in lung diseases and beyond.  DS: Can you provide some background to the company? MT: We are a core imaging laboratory using deep-learning and analytics… Read More

#Exclusive Content

#Adverse event #Cancer research #CAR-T #Cardio #CRISPR #CRISPR-Cas9 #Drug discovery #Gene editing #Imaging #Oncology #Screening

New podcast: Innovation enabled by new drug discovery technologies

This is the latest episode of the free DDW narrated podcast, titled “Innovation enabled by new drug discovery technologies”, which covers two articles written for DDW Volume 24 – Issue 3, Summer 2023. They are called: “CRISPR breakthroughs: New solutions for common diseases” and “Re-assessing the risks of… Read More

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