Genomics

Listen to this article on the DDW Podcast: Slavé Petrovski and Andrew Harper, Centre for Genomics Research, AstraZeneca, outline the implications and insight offered by the recent publication of an AstraZeneca-authored paper “Rare variant contribution to human disease in 281,104 UK Biobank exomes”.  In August 2021, Nature published the largest and most comprehensive evaluation of the role rare genetic variants have […]

Listen to this article on the DDW Podcast: The Covid-19 Host Genetics Initiative carried out one of the largest genome-wide association studies ever. It involved meta-analysis of nearly 50,000 Covid-19 patients and two million uninfected controls. Dr Hamdi Mbarek, Lead Analyst of the Qatari dataset explains how the initiative improved knowledge of host-genetic determinants of Covid-19 […]

GlaxoSmithKline (GSK) and the University of Oxford have announced a five-year collaboration to establish the Oxford-GSK Institute of Molecular and Computational Medicine, which will be based at the University of Oxford and improve the success and speed of research and development of new medicines, building on insights from human genetics and using advanced technologies such […]

The Comprehensive Resistance Prediction for Tuberculosis International Consortium (CRyPTIC) research project has reportedly collected the largest ever global dataset of clinical M. tuberculosis samples from across the world consisting of 15,211 samples from 27 countries on five continents.  Using a new quantitative test for drug resistance and a new approach which identifies all the genetic […]

Researchers at Purdue University and Houston Methodist Research Institute have created a novel strategy for developing an effective vaccine for a widespread form of tuberculosis.  Mycobacterium tuberculosis (Mtb) is a leading cause of death worldwide, leading to over 1.5 million fatalities annually. Approximately one-third of the global population is infected with the latent form of Mtb. […]

Listen to this article on the DDW Podcast: Dr Bongcho Kim is the new CEO of Macrogen Europe, a Netherlands-based provider of genomic sequencing services. Dr Kim’s appointment comes at a time of sustained growth for the company, which is benefitting from the rapidly expanding sequencing market. He talks to Lu Rahman and explains the important […]

Dotmatics has announced its support of the AWS for Health initiative from Amazon Web Services (AWS), which aims to improve laboratory efficiency and accelerate the pace of scientific innovation by facilitating more rapid data access, analysis and exchange between scientists worldwide. AWS for Health is an initiative featuring services and solutions built for healthcare, biopharma, […]

Last year scientists from around the world undertook genetic analysis to uncover the genetic factors influencing why some Covid-19 patients develop severe, life-threatening disease requiring hospitalisation, while others escape with mild symptoms or none at all. A comprehensive summary of their findings to date, published in Nature, reveals 13 loci, or locations in the human […]

Listen to this article on the DDW Podcast: By Andrew Gane, Diagnostics Strategy & Technology Manager, Cytiva A cell is a base unit in biology where the genome is transcribed and translated into function. Our traditional understanding of cells rests heavily on studying cells in tissues as an identical population, with thousands or even millions of […]

ERS Genomics and Setsuro Tech have announced a non-exclusive license agreement granting Setsuro Tech access to ERS Genomics’ CRISPR/Cas9 patent portfolio for Japan. Setsuro Tech has developed a high-throughput genome editing method for mammalian embryos, termed genome editing by electroporation of Cas9 protein (GEEP). Using this method, the company is able to generate genetically engineered […]