Dr James Taylor, Senior Scientist in Cell Line Development at Samsung Biologics, speaks with DDW’s Megan Thomas about how to address the challenges in meeting complex molecule requirements, regulatory standards, and environmental sustainability. Benefits for developers The biopharmaceutical industry has seen a surge in demand for drugs that treat… Read More
DDW’s Megan Thomas examines the value and impact of cell line development in the drug discovery industry. When it comes to the creation of biologics, cell line development is an essential drug discovery process. From a functional perspective, when it comes to monoclonal antibodies (mAbs), enzymes, or other therapeutic proteins,… Read More
DDW’s Megan Thomas speaks to Dr Lucas Thompson, Senior Director of Research at Tune Therapeutics, about the advancements in cell line development and how biotechnologies can enhance the precision and efficiency of therapeutic protein production. MT: What are the benefits cell line development is bringing to biopharmaceutical developers? LT: For… Read More
Axol Bioscience has fully acquired Phenocell, though financial terms of the agreement were not disclosed. The acquisition extends Axol’s portfolio of iPSC-derived cell models, adding skin and human retinal iPSC-derived cell lines to its existing neuroscience, pain and touch, and cardiovascular products and services. Read More
Download the exclusive Guide and read about: What are the benefits cell line development is bringing to biopharmaceutical developers? What technological advances are helping drive efficiencies in cell line development? How is this process underpinning drug development and why is the market growing? In what ways is cell line development… Read More
Reece Armstrong offers an overview of cell line development and outlines the benefits the technology is bringing to biopharmaceutical developers. Cell line development is an essential underpinning of the drug development process, enabling teams to test, optimise and manufacture therapeutics at a commercial scale. It is a crucial for the… Read More
Roxana McCloskey, Senior Global Marketing Manager, Protein Therapeutics, SCIEX explores how innovative analytical approaches can help improve stability for cell line development. Cell line development (CLD) is a critical stage in the early production of biotherapeutic molecules. During the CLD stage, a key goal is to… Read More
This article is sponsored by Revvity. By Anis H Khimani, PhD, Senior Strategy Leader, Life Sciences strategy group, Revvity, Inc. Across the biotherapeutics workflow The landscape of large molecule drug development has evolved significantly in recent decades. As the significance of large molecules… Read More
This is the latest episode of the free DDW narrated podcast, “Challenges and tactics for transformative drug development”. It covers two articles written for Volume 23, Issue 2 – Spring 2022 of DDW. They are called “Balancing speed and quality in CLD for faster drug development”, and… Read More
Generation of a highly expressing, regulatory acceptable clonal cell line is the first key activity in the development of a biopharmaceutical. Cell line development is labour intensive, time consuming and costly and is subject to stringent regulations to ensure patient safety. Dr Jonathan H Dempsey All cell lines used to… Read More
Contract manufacturing organisation (CMO) KBI Biopharma and cell line development company Selexis have opened an integrated facility in Geneva, Switzerland. The integrated KBI/Selexis state-of-the-art facility builds upon the companies’ existing market foothold by combining best-in-class cell line development (CLD) and expert mammalian cell manufacturing in a single… Read More
Listen to this article on the DDW Podcast: As Chief Technical Lead and a Head of R&D at Samsung Biologics America, Soojin Han examines the challenges, tactics, and best partnering practices in cell line development (CLD). She emphasises the need to ensure a balance between shortening commercial CLD timelines,… Read More
The Olympus Provi CM20 incubation monitoring system can be used to develop methods for efficient quality control and data management within your cell culture workflow. The company has created an application note which will allow you to understand how the quantitative data collected from the CM20 enabled users to compare… Read More
