Cell lines

This article is sponsored by Revvity. By Anis H Khimani, PhD, Senior Strategy Leader, Life Sciences strategy group, Revvity, Inc. Across the biotherapeutics workflow The landscape of large molecule drug development has evolved significantly in recent decades. As the significance of large molecules continues to broaden across diverse modalities, emphasis on bispecific and multispecific antibodies […]

This is the latest episode of the free DDW narrated podcast, “Challenges and tactics for transformative drug development”. It covers two articles written for Volume 23, Issue 2 – Spring 2022 of DDW. They are called “Balancing speed and quality in CLD for faster drug development”, and “Sitting down with BridgeBio Pharma”. In the first article, Soojin Han, Chief Technical Lead […]

Generation of a highly expressing, regulatory acceptable clonal cell line is the first key activity in the development of a biopharmaceutical. Cell line development is labour intensive, time consuming and costly and is subject to stringent regulations to ensure patient safety. All cell lines used to produce clinical batches of biopharmaceuticals are required to conform […]

Contract manufacturing organisation (CMO) KBI Biopharma and cell line development company Selexis have opened an integrated facility in Geneva, Switzerland.  The integrated KBI/Selexis state-of-the-art facility builds upon the companies’ existing market foothold by combining best-in-class cell line development (CLD) and expert mammalian cell manufacturing in a single location. The facility will leverage the companies’ expertise […]

Listen to this article on the DDW Podcast: As Chief Technical Lead and a Head of R&D at Samsung Biologics America, Soojin Han examines the challenges, tactics, and best partnering practices in cell line development (CLD). She emphasises the need to ensure a balance between shortening commercial CLD timelines, increasing efficiencies and maintaining product quality. Advances […]

The Olympus Provi CM20 incubation monitoring system can be used to develop methods for efficient quality control and data management within your cell culture workflow. The company has created an application note which will allow you to understand how the quantitative data collected from the CM20 enabled users to compare and detect variable efficiency of […]