Biology

The first DNA synthesised using Evonetix’s semiconductor chip technology has been delivered to the Department of Chemical Engineering and Biotechnology at the University of Cambridge. The DNA was delivered to Dr Jenny Molloy, Co-chair of the Engineering Biology Interdisciplinary Research Centre at the University of Cambridge. The company’s desktop DNA synthesis platform is designed to […]

SLAS Europe has revealed details of the Biology Unveiled track at the upcoming meeting in Brussels, Belgium on May 23-26. The other three tracks are Frontiers in Technology, Shaping the Future of Therapeutics and Bio-Entrepreneurship in Europe. The Biology Unveiled track will feature scientific sessions focusing on the hot topic of personalised medicine, along with […]

Granular Therapeutics, a UK-based biotech company specialising in precision biologic therapies for treating mast cell driven disorders, announced clinical candidate selection for its lead programme which has demonstrated promising results in initial preclinical studies.  Granular Therapeutics has now commenced proof-of-concept (POC) and IND-enabling studies as it prepares for clinical development.   Since starting work on these […]

Ahead of this year’s SLAS2023 conference in San Diego (which takes place 25 February – 1 March) DDW’s Megan Thomas narrates articles from the DDW SLAS2023 supplement as part of the DDW Events podcast series. This is episode three, Connecting lab automation to decision-making. In this episode, we hear from Ashwin Pillai, a Test Engineer […]

This is the latest episode of the free narrated DDW podcast, “CROs and targeted protein degradation offer an exciting future”. It covers two articles written for Volume 23, Issue 1 – Winter 2021/22 of DDW. They are called “CROs: Drug discovery expertise on hand” and “Why the emergence of targeted protein degradation is so exciting”. […]

This is the latest episode of the free DDW podcast, “The role of animals in the future of drug discovery”. It covers two articles written for Volume 22, Issue 4 – Fall 2021 of DDW, narrated by DDW Multimedia Editor Megan Thomas. They are called “How an animal model provider can save your resources” and […]

The drug discovery sector is working to address cancer disparities. Anita Ramanathan examines the importance of inclusivity and diversity throughout the drug discovery and development process.  While the risk of cancer is universal, some groups are disproportionately affected by cancer compared to others. Disparities resulting from genetic, environmental, social, and economic factors increase cancer risks […]

Single cell and spatial tools from 10 X Genomics are designed to deliver powerful, multiomic insights from complex disease samples that enable you to confidently fuel your target identification pipeline with the most promising candidates. Resolving complex biology with single cell and spatial multiomics was presented by Stephen Hague, Managing Lead Science & Technology Advisor […]

Biotechnology company Galapagos will in-license drug targets for inflammatory bowel disease (IBD) which were discovered using a biology platform developed by Scipher Medicine. The move follows a deal Galapagos and Scipher Medicine made in 2020 to jointly validate a suite of novel IBD targets discovered by Scipher’s Spectra platform. Under the deal, Galapagos had the […]

This decade is the age of the biobank, says Lauren Taylor, a scientist and solutions manager in Digital Sciences at Thermo Fisher Scientific. She shares her thoughts on the importance of IoT and LIMS with DDW. Never have we seen such investment, growth and interest in the meticulous collection of human tissue, fluids and genetic […]

Listen to this article on the DDW Podcast: Last year a new translational research centre was established to bolster the University of Dundee’s drug discovery position. The Centre for Targeted Protein Degradation (CeTPD) would allow Professor Alessio Ciulli and colleagues to expand their pioneering work in an area that has attracted billions of pounds of investment. Maria Wallace finds out […]

Alamar Biosciences, a proteomics platform, and Abcam, innovators in life sciences research tools, have partnered to further their understanding of the human proteome.  Proteomics  The field of proteomic analysis is in the spotlight. Its advance not only enhances the understanding of fundamental biology, but also sheds light on the status of human health and disease. […]

Quris, an artificial intelligence (AI) company in the pharmaceutical industry, has launched a clinical prediction AI platform to predict which drug candidates will safely work in humans. This will improve efficacy and cut drug development costs.   What do they do?  Quris uses AI-powered miniaturised “patients-on-a-chip” to avoid the risks and costs of failed clinical trials and eliminate […]

A new peer-reviewed article demonstrated that Hesperos’ Human-on-a-Chip (HoaC) cell-based neuromuscular junction (NMJ) platform system can mimic the disease phenotypes of myasthenia gravis (MG). The manuscript, titled “A Functional Human-on-a-Chip Autoimmune Disease Model of Myasthenia Gravis for Development of Therapeutics,” was published in Frontiers in Cell and Developmental Biology.  Context  There is an unmet need […]

CN Bio has entered a research collaboration with the Infection Innovation Consortium (iiCON) to validate the next generation of Covid-19 research tools.  iiCON’s £174 million programme brings together industry, academia, and clinicians to accelerate the discovery, development and deployment of new treatments and products. Led by the Liverpool School of Tropical Medicine (LSTM), its partner members include Unilever, […]

Metabolon’s first offering from its SmartPanel portfolio aims to provide drug discovery and precision medicine researchers with a novel, dynamic process to explore biologically relevant views of metabolomic data in the context of specific metabolic pathways, biological themes, and disease associations.  “The metabolome offers a window into human biology, providing insights on the human body’s response to chemicals and […]