New products to expand the horizons of single cell research

Bruker has launched new products, as outlined June 1-3, 2021 at the eXceed Symposia 2021. The products include timsTOF trueSCP and timsTOF Pro 2.

Mass spectrometric proteomics has become a staple of modern research in understanding biological function and disease mechanisms. Healthy or diseased tissues that seem homogenous are composed of cells with a variety of different proteomes. Deciphering the proteome of each single cell is key to fully understanding its function and has traditionally presented a major challenge.

Following the introduction of 4D-Proteomics, Bruker has launched the timsTOF trueSCP. With a new ion source concept for five times greater ion-transfer together with the TIMS based time-focusing effect and higher fidelity separation of noise from signal as well as the proven acquisition speed in PASEF (> 100 Hz), the timsTOF trueSCP is unique in its class.

Introducing the timsTOF Pro 2 mass spectrometer with Bruker’s newest generation dual-TIMS analyser offers three times higher ion capacity. Simplified ion optics maximise ion transfer and sensitivity to set a new standard in 4D-Proteomics. The product offers uncompromised depth of coverage with short gradients, and CCS-enabled precision which makes the timsTOF Pro 2 key for translational multiOmics applications.

Professor Matthias Mann, Director at the Department of Proteomics and Signal Transduction, Max-Planck-Institute of Biochemistry, commented: “I always said that single cell proteomics would not happen in my lifetime, but I’m happy to have been proven wrong.”

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