Author Archives: Megan Thomas

#Biotechnology #Cancer research #Drug discovery #Tumours

This week in Drug Discovery (20-24 July 2026) 

News round-up for 20-24 July by Megan Thomas, Content Team at DDW.  This week’s news roundup highlights the latest advances in cancer research and treatment, from promising clinical trial updates to discoveries that could improve the body’s immune response to tumours. The top stories include progress in… Read More

#News

Protein degrader
#Avenue Biosciences #Circio Holding #Disease treatment #Gene therapy #Proteins #Synergistic technology

Research collaboration to enhance protein secretion for gene therapy 

Circio Holding and Avenue Biosciences have entered a research collaboration to combine their synergistic technologies to improve long-term expression of secreted proteins, relevant for treatment of a broad range of diseases.  Secreting proteins from cells into surrounding tissue, or into circulation, opens new treatment opportunities beyond classical gene therapy for… Read More

#News

#Cancer immunotherapies #Cancer research #Dendritic cells #Icahn School of Medicine at Mount Sinai #Tumour biology

Dendritic cells found to organise cancer-fighting immune hubs 

Researchers at the Icahn School of Medicine at Mount Sinai have identified a specialised immune cell that builds and maintains powerful immune hubs inside tumours, a discovery that could help improve the effectiveness of cancer immunotherapies.  The findings, published in Science, show that dendritic cell type 1 is essential for… Read More

#News

Human kidneys
#Biotechnology #Clinical stage biotechnology #Drug discovery #Funding #Rege Nephro #Regenerative Medicine

Rege Nephro secures US$10.6m for ADPKD and beyond

Rege Nephro, a Japanese clinical-stage biotechnology company focused on iPS cell-based kidney regenerative medicine and drug discovery, has closed a financing round totalling approximately US$10.6 million. Through the issuance of Japan-Keep It Simple Security (J-KISS) share acquisition rights, proceeds are expected to support commercialisation activities for RN-014, the company’s lead… Read More

#News

Breast cancer cell
#Breast cancer #Cancer therapeutics #Clinical trials #Intensity Therapeutics #intratumoural cancer therapies #Tumours

Phase II triple-negative breast cancer trial restarts

Intensity Therapeutics has administered INT230-6 in the INVINCIBLE-4 Study in Switzerland. The clinical biotechnology company is focused on the discovery and development of novel intratumoural cancer therapies that are designed to kill tumours and increase immune system recognition of cancers using its proprietary non-covalent conjugation technology. The trial (NCT06358573) analyses… Read More

#News

#Alzheimer's #Alzheimer's Drug Discovery Foundation #Biomarkers #Drug discovery #Parkinson's #Partnership #The Michael J Fox Foundation #The Michael J Fox Foundation for Parkinson’s Research (MJFF)

US$5m partnership targets Alzheimer’s and Parkinson’s biomarkers

The Alzheimer’s Drug Discovery Foundation’s (ADDF) Diagnostics Accelerator (DxA) and The Michael J. Fox Foundation (MJFF) have announced a new US$5 million partnership to accelerate the development of minimally invasive biomarkers for measuring pathologies associated with Parkinson’s and Alzheimer’s diseases. Isobel Coleman, Chief Executive Officer of the Alzheimer’s Drug Discovery… Read More

#News

#Cambridge Omics Centre #Drug discovery #Metabolomics #Multiomics #Novogene Europe

Novogene Europe launches untargeted metabolomics service

Multiomics research services partner Novogene Europe has launched its Untargeted Metabolomics Service through its Cambridge Omics Centre. This new capability will help researchers across the UK and Europe to connect molecular data with biological function by adding metabolite-level insight to genomics, transcriptomics, microbiome and broader life science studies. Untargeted Metabolomics… Read More

#News

#Drug discovery #Drug Discovery Innovators & Investors #Events #Innovation #Innovators & Investors #Investment

Introducing the Drug Discovery Innovators & Investors Event Series

We’re excited to announce the launch of Drug Discovery Innovators & Investors (DDII) – a new event series from Drug Discovery World. The three-part global event series focuses on technology, innovation, and investment in early-stage drug discovery. Bringing together senior executives, R&D leaders, lab managers, and decision-makers from pharma and… Read More

#Editor's Choice #News

#Automation #Automation / robotics #Drug discovery #Lab technology #Webinar

Last chance to register: Moving beyond siloed automation in an orchestrated lab

Many laboratories have invested in automation, yet workflows often remain fragmented, with disconnected instruments, data, and processes creating inefficiencies and limiting scalability. As scientific workflows grow more complex, automation alone is no longer enough. Leading labs are now embracing orchestration, the coordination of instruments, robotics, software, data, and people across… Read More

#News

Microplate
#Automation #Automation / robotics #Drug discovery #Lab technology #Webinar

Register to explore the orchestrated lab: Moving beyond siloed automation

Many laboratories have invested in automation, yet workflows often remain fragmented, with disconnected instruments, data, and processes creating inefficiencies and limiting scalability. As scientific workflows grow more complex, automation alone is no longer enough. Leading labs are now embracing orchestration, the coordination of instruments, robotics, software, data, and people across… Read More

#News

#AstraZeneca #Drug discovery #Life sciences #o2h #o2h Discovery #o2h Group #o2h Ventures

CWOW and the future of integrated drug discovery

Held from 11–19 June 2026, CWOW welcomed more than 5,000 attendees across 37 venues, delivering over 280 sessions and bringing together investors, entrepreneurs, academics, policymakers, operators, local communities and the wider biotech and techbio community from across the UK and beyond. Read more about the event here. Below, DDW… Read More

#Exclusive Content

KRAS
#Champions Oncology #Drug discovery #KRAS #Oncology #Patient-derived tumour models #Tumour models #Webinar

Webinar explores resistance to Pan-RAS(ON) inhibition

KRAS mutations are among the most prevalent oncogenic drivers in solid tumours, yet predicting which patients will respond to targeted therapy — and understanding why resistance inevitably emerges — remains one of the central challenges in oncology drug development. ‘Cracking KRAS: Decoding Sensitivity and Resistance to Pan-RAS(ON) Inhibition Across Patient-Derived… Read More

#News

Lab automation
#Automation #Automation / robotics #Drug discovery #Lab technology #Webinar

Learn more about lab workflow scheduling and orchestration

Many laboratories have invested in automation, yet workflows often remain fragmented, with disconnected instruments, data, and processes creating inefficiencies and limiting scalability. As scientific workflows grow more complex, automation alone is no longer enough. Leading labs are now embracing orchestration, the coordination of instruments, robotics, software, data, and people across… Read More

#News

Test for KRAS mutation
#Champions Oncology #Drug discovery #KRAS #Oncology #Patient-derived tumour models #Tumour models #Webinar

Lessons from 50+ patient-derived KRAS-mutant tumour models

KRAS mutations are among the most prevalent oncogenic drivers in solid tumours, yet predicting which patients will respond to targeted therapy — and understanding why resistance inevitably emerges — remains one of the central challenges in oncology drug development. ‘Cracking KRAS: Decoding Sensitivity and Resistance to Pan-RAS(ON) Inhibition Across Patient-Derived… Read More

#News

Automation
#Automation #Automation / robotics #Drug discovery #Lab technology #Webinar

Webinar: Moving beyond siloed automation with an orchestrated lab

Many laboratories have invested in automation, yet workflows often remain fragmented, with disconnected instruments, data, and processes creating inefficiencies and limiting scalability. As scientific workflows grow more complex, automation alone is no longer enough. Leading labs are now embracing orchestration, the coordination of instruments, robotics, software, data, and people across… Read More

#News

#Champions Oncology #Drug discovery #KRAS #Oncology #Patient-derived tumour models #Tumour models #Webinar

Decoding Pan-RAS(ON) inhibitor activity across KRAS models: Webinar

KRAS mutations are among the most prevalent oncogenic drivers in solid tumours, yet predicting which patients will respond to targeted therapy — and understanding why resistance inevitably emerges — remains one of the central challenges in oncology drug development. ‘Cracking KRAS: Decoding Sensitivity and Resistance to Pan-RAS(ON) Inhibition Across Patient-Derived… Read More

#News