Author Archives: Megan Thomas

#AACR #AACR 2023 #Awards #Cancer immunotherapy #Cancer research #Immunology / Virology & Vaccines

Monday 17 April at AACR Annual Meeting 2023

DDW’s Megan Thomas rounds up highlights from Monday 16 April at AACR 2023, from promising trial results for colorectal cancer patients to updates on Biden’s Cancer Moonshot initiative. Clinical announcements  Data on colorectal cancer patients with African ancestry Today, data presented at the AACR Annual Meeting showed that genomic… Read More

#News

#AACR #AACR 2023 #Awards #Cancer immunotherapy #Cancer research #Immunology / Virology & Vaccines #mRNA

Sunday 16 April at AACR Annual Meeting 2023

DDW’s Megan Thomas rounds up highlights from Sunday 16 April at AACR 2023, from promising trial results for a personalised mRNA-based cancer vaccine to winners of lifetime achievement awards. Opening plenary session Sunday’s opening plenary session borrowed its name from the Annual Meeting theme, “Advancing the Frontiers of Cancer Science… Read More

#News

#AACR 2023 #Cancer #Cancer immunotherapy #Cancer research #Oncology #Therapeutics

Eight announcements to expect at AACR 2023   

The American Association for Cancer Research (AACR) Annual Meeting is taking place at the Orange County Convention Center in Orlando, Florida from April 14-19, 2023. As the theme, Advancing the Frontiers of Cancer Science and Medicine, suggests, a number of announcements, results and presentations will take place… Read More

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Antibody drug conjugate
#AI / data analytics / healthtech / informatics #Antibodies #Antibody drug conjugate (ADC) #Big pharma #Drug development #Precision medicine

A personal view on antibody drug development

Oliver Schon, PhD, is VP Research & Development at BiVictriX Therapeutics, a UK-based emerging drug discovery and development company generating a pioneering first-in-class next-generation ADC anti-cancer therapeutics which exhibit superior selectivity towards cancer. Dr Schon is applying his broad expertise from lead discovery to manufacture in order to progress differentiated,… Read More

#Exclusive Content

#Astex Pharmaceuticals #Covid-19 #Drug discovery #Life sciences #Public health

Sitting down with… Dr Harren Jhoti, Astex Pharmaceuticals

Listen to this article on the DDW Podcast: Following his recent OBE, Diana Spencer speaks to Dr Harren Jhoti about his career, the UK life sciences sector, fragment-based drug discovery and what the future holds for the industry. At the end of 2022, Astex Pharmaceuticals co-founder, President and CEO Dr Harren… Read More

#Cancer Research #Exclusive Content

#Cancer immunotherapy #Immunology / Virology & Vaccines #Moderna #mRNA #mRNA-based vaccines #Tumour biology

Vaccine for the ‘previously undruggable’ just a decade away 

In an exclusive interview with The Guardian, Moderna said that cancer and heart disease vaccines would be ready by 20301. The pharmaceutical firm also provided promising updates on mRNA-4157/V940, which targets different tumour types, at Moderna’s Vaccines Day on 24 March 20232.   The… Read More

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Asthma inhaler
#Asthma #AstraZeneca #Clinical trial #National Institute for Health and Care Excellence (NICE) #NHS England

Add-on treatment for severe uncontrolled asthma approved 

The National Institute for Health and Care Excellence (NICE) has issued final draft guidance recommending AstraZeneca’s Tezspire (tezepelumab).  The drug is approved for use within NHS England and NHS Wales and as add-on maintenance therapy in adult and adolescent patients, 12 years and older, with severe asthma… Read More

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#Cancer research #Clinical research #Clinical trial #Drug discovery #Oncology #Phase I trial #Phase II trial

Podcast shares industry highlights for 3-7 April

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates.  The headlines this week have revealed a high level of clinical trial activity taking place… Read More

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#DDW Highlights podcast

DDW Highlights: 11 April 2023

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates.  The headlines this week have revealed a high level of clinical trial activity taking place… Read More

#Podcasts

#AACR #Cancer research #Drug development #Drug discovery #Events

Looking ahead to AACR  

Ahead of attending the American Association for Cancer Research (AACR) annual meeting from 14-19 April, 2023 at the Orange County Convention Center in Orlando, Florida, DDW’s Megan Thomas outlines what to expect from the event.   Programme highlights   The topic tracks include everything from clinical trials, drug development, immunology and bioinformatics,… Read More

#Cancer Research #Exclusive Content

#AI / data analytics / healthtech / informatics #Lab automation #Laboratory data #SLAS2022

Podcast on data integrity and the value of the cloud

This is the latest episode of the free DDW podcast, “Data integrity and the value of the cloud”. It covers two articles written for the exclusive DDW & SLAS2022 supplement published in Volume 23, Issue 1 – Winter 2021/22 of DDW. They are called “The concept of data… Read More

#News

#Narrated podcasts

Data integrity and the value of the cloud

This is the latest episode of the free DDW narrated podcast, “Data integrity and the value of the cloud”. It covers two articles written for the exclusive DDW & SLAS2022 supplement published in Volume 23, Issue 1 – Winter 2021/22 of DDW. They are called “The concept of data integrity”… Read More

#Podcasts

#Biologics #Biology #Biotechnology #Drug development #Therapeutics

Next-generation pipeline for treating mast cell driven diseases 

Granular Therapeutics, a UK-based biotech company specialising in precision biologic therapies for treating mast cell driven disorders, announced clinical candidate selection for its lead programme which has demonstrated promising results in initial preclinical studies.  Granular Therapeutics has now commenced proof-of-concept (POC) and IND-enabling studies as it prepares… Read More

#News

#Brain cancer #Cancer research #Childhood cancer #Clinical trials #Paediatrics

CureSearch to fund Phase I clinical trial for paediatric brain cancer 

CureSearch for Children’s Cancer, a national non-profit with a mission to end childhood cancer by driving targeted and innovative research in an accelerated time frame, will fund a Phase I clinical trial to bring new therapies to paediatric brain cancer patients, including those with limited or no treatment options. Read More

#Cancer Research #News

Heart
#Clinical trial #Heart failure

Phase I study observes positive results for heart failure 

Sequana Medical, a company treating fluid overload in liver disease, heart failure and cancer, has announced positive results from its Phase I single-centre, single-arm, single-dose trial (CHIHUAHUA) with its second-generation DSR product (DSR 2.0).   The purpose of the trial was to evaluate the safety and tolerability profile… Read More

#News

#Biopharmaceuticals #Collaboration #Contract Research Organisations (CROs) #Cryo-EM #Drug research #Immunology #Oncology

What’s next for this integrated drug discovery collaboration? 

Galapagos and NovAliX have entered a strategic collaboration in which Galapagos’ research and discovery capabilities and exclusively related employees based in Romainville, France, will be transferred to NovAliX, a drug discovery-focused Contract Research Organisation. The agreement follows Galapagos’ renewed focus on its key therapeutic areas of oncology and… Read More

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