2005 Archive

COX-2 Inhibitor Toxicity – Warning Shot Over Pharma’s Bow
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Overview of Biomarkers in Disease, Drug Discovery and Development
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Exposure Response Modelling – A Safe and Profitable Way to Speed Drugs to Market
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The Impact of RNAi on Drug Discovery
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The Search for Validated Biomarkers in the Face of Biosystems Complexity
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Compound Management – In Pursuit of Sample Integrity
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Cryo Electron Microscopy and Electron Tomography Will Play a Crucial Role in the Future of Drug Development
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Patent Pools as a Solution to the Licensing Problems of Diagnostic Genetics
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Discovery is Not Enough – How a New Compliance Agenda is Changing the Face of the Industry
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Ion Channels – New Opportunities for an Established Therapeutic Target Class
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Creating a Productive R&D Culture
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High Content Screening – Emerging Importance of Novel Reagents/Probes and Pathway Analysis
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The Next Decade of Gene Expression Profiling
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Computer-Aided Design: Progress Towards More Rational Drug Discovery
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Nanotechnology Approaches to Solving the Problems of Poorly Water-Soluble Drugs
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Ontologies – Semantic Networks of Pharmaceutical Knowledge
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Redefining Drug Discovery Informatics
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Engineering Success – Wyeth Redefines Its Research and Development Organisation
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The Future of the CRO Industry
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Immunomodulation – Emerging From Obscurity into a Major Therapeutic Class
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Applying the Semantic Web to Drug Discovery and Development
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Outsourcing Life Science Innovations With University Technology Transfer
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New Options for Cell-Based Assay Automation
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Advances in the Imaging of Biomolecules: The Label-Free Intrinsic Imaging Approach
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The Market for RNA Purification Products and Services
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The Role of the Medicinal Chemist in the Drug Discovery Process: Current Status and Future Prospects
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Personalised Medicine – What’s in it for Big Pharma?
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The Time is Right for Labs to Embrace the Principles of Industrial Automation
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Building a uHTS Laboratory
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Next Generation HIV Drugs Move into Late Stage Development
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High Throughput Screening – Meeting the Challenges of More Cell-Based Assays and HCS
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Automated Patch Clamping – Setting a New Standard for Early hERG
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Development of an HTS FabD Inhibition Assay Using a New 384-well Filter Plate to Screen Novel Antibodies
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