Tiziana Life Sciences

Monoclonal antibodies
#Monoclonal antibodies #Multiple sclerosis #Phase II trial #Tiziana Life Sciences #University of Massachusetts

UMass joins Phase II trial for multiple sclerosis

The University of Massachusetts (UMass) has begun dosing participants with Tiziana Life Sciences’ lead development candidate, intranasal foralumab, as part of an ongoing Phase II trial in patients with non-active secondary progressive multiple sclerosis (na-SPMS). UMass joins Brigham and Women’s Hospital (BWH), Yale Multiple Sclerosis Center, and Johns… Read More

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Human liver
#Cardiometabolic diseases #GLP-1 #Monoclonal antibodies #Obesity #Tiziana Life Sciences

Ozempic and antibody combination restores liver homeostasis

New study results have demonstrated the anti-inflammatory potential of Tiziana Life Sciences’ anti-CD3 antibody foralumab in combination with semaglutide (Ozempic/Wegovy). The data show that the combination of nasal anti-CD3 plus semaglutide improves liver homeostasis and reduces inflammation in models of diet-induced obesity (DIO). Read More

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Monoclonal antibodies
#Monoclonal antibodies #Tiziana Life Sciences #Type 1 diabetes

Tiziana develops intranasal antibody for type 1 diabetes

Biotechnology company Tiziana Life Sciences is initiating a programme to develop intranasal foralumab for the treatment or prevention of type 1 diabetes. “With the FDA approval of the humanised anti-CD3 mAb TZIELD (teplizumab-mzwv injection) and then its subsequent announced acquisition of Provention Bio by Sanofi for… Read More

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