Stroke

Patient holding pill in hand
#Clinical trial #Combination therapy #Stroke

Combination therapy pill could reduce stroke risk by 40% 

A single pill low-dose combination therapy could reduce the risk of recurrent stroke by almost 40%, trial results show.  GMRx2, developed by biopharmaceutical company George Medicines, reduced recurrent stroke risk in patients with previous intracerebral haemorrhage (ICH) by 39% compared to placebo, according to results published in the New… Read More

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A laboratory mouse
#ischaemic stroke #Stroke #The University of Manchester

Clot-busting drug could harm stroke treatment response 

A clot-busting drug may stop promising stroke medicine from working properly, research reveals.  Researchers at the University of Manchester found the clot-busting therapy, known as tissue plasminogen activator (tPA), interacts negatively with the anti-inflammatory treatment anakinra, highlighting the need for new stroke therapies alongside existing standard care. Read More

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Professor Glenn King working in the lab with a funnel web spider. Credit The University of Queensland
#Australia #Heart attack #Stroke #University of Queensland

Spider venom peptide trialled as cardiovascular treatment 

A potential treatment for heart attack and stroke derived from spider venom has been administered to the first participants in clinical trial.  A team of researchers from the University of Queensland, Australia published preclinical analysis showing the protein Hi1a could treat heart attack and stroke patients. The… Read More

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Blood cells
#ischaemic stroke #Preclinical investigations #Stroke #The University of Manchester

New drug a potential breakthrough for stroke treatment

A new clot-busting drug has been shown in preclinical investigations to be significantly better at treating ischaemic stroke than existing therapies.  The compound, known as caADAMTS13, could be a breakthrough for patients who have brain blood clots with an overabundance of platelets.  The study, funded… Read More

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Red blood cells
#Bioxodes #Phase II trial #Stroke

Positive data for intracerebral haemorrhagic stroke drug

Bioxodes has shared promising interim results from the BIRCH Phase IIa clinical trial of its lead asset, BIOX-101, to treat intracerebral haemorrhagic stroke (ICH).  Interim analysis from the first 16 patients in the trial showed that primary safety and secondary efficacy endpoints were met.   “While… Read More

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Brain Awareness Week
#Brain #Brain Awareness Week #Brain disease #Dementia #Drug discovery #Parkinson's #Stroke

Brain Awareness Week: the wonders of brain science

DDW’s Diana Spencer reviews some of the advances in drug discovery for diseases of the brain in the last month. Brain Awareness Week is an annual global campaign that takes place from March 13-19, aimed at raising awareness and support for brain science and issues related… Read More

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Patient receiving flu vaccine
#Flu vaccine #ischaemic stroke #Stroke

Flu vaccine linked to lower risk of stroke

Getting an annual flu shot may be associated with a lower risk of stroke, Spanish researchers have claimed. The findings, from a study conducted at the University of Alcalá in Madrid, have been published in the journal Neurology. The observational study suggests that those who have a flu shot have… Read More

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