Medical Research Council

#Aging Cell #Cellular stress #Francis Crick Institute #Imperial College London #Medical research #Medical Research Council #MRC Laboratory of Medical Sciences #Queen Mary University of London #University of Cologne #University of Lyon

Drug extends animal life by activating ‘energy saver’ mode 

Scientists have successfully used a drug to prolong the lifespan of several species of animals, in some cases by more than 25%.  The study, published in Aging Cell, found strong evidence that triggering a protein, governing energy levels, may help organisms live significantly longer. … Read More

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Genetics researcher
#Genetic diseases #Genetics / genomics #Investment #Medical Research Council

New multi-million pound UK centre to research fatal genetic diseases

The UK’s Medical Research Council has invested £50 ($67.3) million into the study of mitochondrial diseases for improved treatments.   The new MRC Centre of Research Excellence in Mitochondrial Genome Therapeutics brings together leading experts from across disciplines to define how mutations in mitochondrial DNA (mtDNA) cause disease… Read More

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Laboratory research
#Clinical trial design #Clinical trials #Medical Research Council #National Institute for Health and Care Excellence (NICE)

£50m UK centre to overhaul clinical trial design

A new UK initiative aims to shake-up approaches to clinical trial design and delivery by developing new ways to speed up the process and drive improvements.  The Medical Research Council Centre of Research Excellence in Clinical Trial Innovation in partnership with the National Institute for Health and… Read More

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Innovation Centre, London
#Medical Research Council #National Institute for Health Research #UK

New £50 million MRC Centre to transform clinical trials 

A new £50 million ($67 million) Medical Research Council Centre is set to overhaul clinical trials for UK patients.  The Medical Research Council Centre of Research Excellence in Clinical Trial Innovation, in partnership with the National Institute for Health and Care Research, will receive up to £50 million ($67 million) over… Read More

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#Age-related diseases (ARDs) #Genetics / genomics #Medical Research Council #National Institute for Health Research #University of Exeter

Genetic study shines light on causes of multimorbidity

The largest genetic study to date into long-term health conditions of later life has identified opportunities for new ways to treat multiple overlapping conditions.    Currently, nine million people in the UK live with two or more long-term conditions at the same time (multimorbidity). Their treatment accounts for… Read More

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Vaccine research
#Innovate UK #Medical Research Council #MHRA #Regulatory #UK

New UK centres of excellence to accelerate delivery of treatments

Seven new Centres of Excellence for Regulatory Science and Innovation (CERSIs) are to receive funding up to £1 ($1.2) million each, to lead the way in safer, faster pathways for innovative medicines and devices.  The centres will be funded by Innovate UK in partnership with the Medicines… Read More

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#Advanced Therapies #Cell and gene therapy #Laboratory #Medical Research Council

MRC launches new £50m UK centres to develop gene therapies

The Medical Research Council (MRC), part of UKRI, is launching its first two Centres of Research Excellence (CoRE), which will develop transformative new advanced therapeutics for currently untreatable diseases.   The new UK centres will receive up to £50 ($63.8) million each over 14 years.  They… Read More

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Jigsaw puzzle of the brain
#Cryo-EM #Dementia #Medical Research Council #Motor neurone disease #Neurodegenerative disorders #Neuroscience

Researchers identify potential drug target for early-onset dementia

Scientists have identified abnormal aggregates of a protein called TAF15 in the brains of individuals with early-onset dementia, known as frontotemporal dementia, where the cause was not previously known. The research led by scientists from the Medical Research Council (MRC) Laboratory of Molecular Biology, in Cambridge,… Read More

#Editor's Choice #News

PET scanner
#Imaging #Innovate UK #Medical Research Council #Medicines Discovery Catapult (MDC) #PET technology #UK

Total-body PET scanners will enhance UK drug discovery

A national total-body positron emission tomography (PET) imaging platform for drug discovery is launching in the UK next year. It is hoped that the National PET Imaging Platform (NPIP) will transform medical research and industrialise cutting-edge technology, enhancing the quality and speed of drug discovery. Read More

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Clinical research
#Biomedical research #Drug discovery #Drug repurposing #LifeArc #Medical Research Council #Medicines repurposing

Toolkit launched for medicines repurposing

A free online toolkit has been launched to help researchers navigate the opportunities and challenges of repurposing medicines for different indications. The toolkit was created by medical research charity LifeArc and the Medical Research Council (MRC). “Having learned the challenges of repurposing firsthand, I think this toolkit is enormously practical… Read More

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