Gout

Chronic gout
#Clinical trial #Crystalys Therapeutics #Gout

Crystalys doses first patients in Phase II gout trial 

Crystalys Therapeutics has dosed the first patients in a Phase II trial evaluating a treatment for difficult-to-treat gout.  The trial will evaluate dotinurad, a next-generation, once daily, oral URAT1 inhibitor with the potential to deliver best-in-class safety and efficacy for the treatment of gout, particularly in patients with limited treatment… Read More

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Chronic gout
#Atom Bioscience #China #Clinical trial #Gout #hyperuricemia #Phase II trial

URAT1 inhibitor controls chronic gout at low doses

Atom Bioscience has revealed positive results from its China Phase IIa clinical trial of ABP-671, its URAT1 inhibitor for chronic gout.  The randomised, double-blind, placebo-controlled trial enrolled 54 patients with gout or  across six cohorts, with seven randomised to ABP-671 and two to placebo per cohort. … Read More

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