According to a 2020 Biotechnology Innovation Organization report, fewer than 8% of drug candidates that enter clinical trials eventually receive regulatory approval. One of the primary reasons for this high failure rate is the poor translatability of preclinical findings, often due to a lack of appropriate mouse models. Read More
This guide explores key considerations for generating and managing genetically engineered mouse models (GEMs) to accelerate and optimise preclinical research programmes. Generating GEMs: three cutting-edge technologies you need to know. Five key components of effective colony management. How integrated solutions can unlock the full potential of preclinical research. Read More
This paid-for advertorial by Taconic Biosciences appeared in DDW Volume 25 – Issue 3, Summer 2024. Harnessing the power of sophisticated GEMs and humanized mice is essential to moving research forward. In the dynamic landscape of drug discovery, the utilisation of high-quality animal models is paramount for success. Among these… Read More
