Drug delivery

Oregon State University College of Pharmacy scientists have shown that lipid nanoparticles and messenger RNA could treat blindness associated with a rare genetic condition.  Researchers developed nanoparticles able to penetrate the neural retina and deliver mRNA to the photoreceptor cells whose proper function makes vision possible.  The study, led by OSU Associate Professor of Pharmaceutical […]

In January 2022, DDW’s Megan Thomas spoke to decision-makers from the drug discovery industry about their predictions on what 2022 holds for our sector. As we head into 2023, DDW will be publishing a series of reflections on these predictions. Here, Thomas reflects specifically on Anita Cooper’s prediction relating to the importance of clinical trials.  […]

Bio-chromatography company Sartorius BIA Separations (BIA) and exosomes medicines company Exopharm have signed a Material Transfer Agreement and associated collaborative programme.  The partnership aims to combine Exopharm’s LEAP technology together with BIA’s CIM (Convective Interaction Media) monolith chromatography for improved large-scale therapeutic exosome production and commercialisation.  The companies hope to meet the demand for a […]

A new polymer-based drug delivery system for mRNA and other nucleic acids has won the CPHI Excellence in Pharma Award in the category “Packaging and Drug Delivery”.  The system was developed by Evonik Health Care together with researchers at Stanford University.  Developed together with Professors Robert Waymouth, Paul Wender and Ronald Levy from the University […]

Ashley Rein, Global Market Manager for Topical Drug Delivery at Lubrizol Life Science Health (LLS Health), explains how by using mucoadhesive drug delivery, developers can bring novel drugs to market and maximise the efficacy of pre-existing APIs.  Drug discovery and development is a time-consuming and costly endeavour. The journey from novel API to final approval […]

Gurmeet Singh, Senior Director at West Pharmaceutical Services & Jeff Kyle, Senior Director of Wearable Delivery Systems explore how a focus on containment in early drug discovery can help ease the development process later on. It may seem counterintuitive to spend time and money on planning for containment and delivery systems for a drug in […]

Pharmaceutical company Transpire Bio will work alongside drug delivery provider Recipharm to develop two inhaled medicines for the treatment of asthma and Chronic Obstructive Pulmonary Disease (COPD).   Transpire Bio announced a definitive agreement with Recipharm to develop its TRB-1 and TRB-2 inhaled medicines. These are the first products developed by Transpire Bio and will be […]

Biotechnology company Calidi Biotherapeutics has been granted a US patent for its SuperNova (SNV) technology platform. Calidi’s SNV platform is composed of allogeneic, adipose-derived mesenchymal stem cells (AD-MSC) loaded with an oncolytic agent. The company aims to use it in combination with various immunotherapy agents, including blocking antibodies. The SNV platform is designed to shield oncolytic viral payloads from the immune system, potentially delivering immuno-oncology […]

Biotech ISA Pharmaceuticals has launched a clinical trial using its Amplivant adjuvant technology which will enable the delivery of a cancer vaccine in patients.  The clinical trial, run by partner Scancell Holdings, is a multicentre clinical trial testing Scancell’s Modi-1 vaccine in patients with triple negative breast cancer, ovarian cancer, head and neck cancer, and […]

Jackson ImmunoResearch, manufacturers of secondary antibodies and immunoreagents for the life science market, has announced a new range of detection reagents for improved image quality.  Nano Secondaries   Jackson ImmunoResearch Nano Secondaries are polyclonal VHH Fragment antibodies (Nanobodies*) produced in Alpacas. They are available with specificity to human, rabbit, or mouse. Ten times smaller than conventional […]