A new agreement grants Novo a global exclusive license to Nanexa’s PharmaShell atomic layer deposition (ALD) drug delivery technology platform for certain therapeutic peptide drugs in indications including obesity, type 2 diabetes and other cardiometabolic diseases. The collaboration includes development of long-acting injectable formulations with different administration-frequency… Read More
Recent discoveries into gut bacteria and nanomedicines could pave the way for better treatments of gut pain, new research suggests. According to studies published in Cell Host & Microbe and Proceedings of the National Academy of Sciences (PNAS), scientists have discovered a new… Read More
JCR Pharmaceuticals and Alexion, AstraZeneca Rare Disease, have entered into a license agreement for JCR’s JUST-AAV capsids to develop genomic medicines. JUST-AAV encompasses a range of vector types optimised for various target tissues—including liver-sparing, muscle-targeting, and brain-targeting variants—to expand the potential of AAV-based gene therapy. … Read More
Scientists have developed a method for analysing the structure of lipid nanoparticles that could be used to improve vaccine and drug delivery. A team led by scientists at the University of Nottingham’s School of Pharmacy demonstrated a new cryogenic mass spectrometry approach for depth profiling frozen lipid… Read More
In the In Conversation With series, a part of the free DDW podcast, DDW speaks with members of the drug discovery industry about their work and how it helps turn science into business. In this episode, Megan Thomas is in conversation with Dimitrios Goundis, CEO… Read More
DDW Editor Reece Armstrong speaks to Ellie Mahjubi, Vice President, Protein and cell analysis at Thermo Fisher Scientific, about how spatial biology is impacting drug discovery and development research. RA: What’s the future and potential for spatial biology? EM: Technological advancements in spatial… Read More
Kimberly Gentile, Senior Vice President of Clinical Operations at Biohaven Pharmaceuticals, explores the importance of newer patient-centric clinical trial strategies that can help enable better outcomes. Drug development is my passion. My 30-year career in the pharmaceutical industry has been spent on the frontline of… Read More
A new Guide is now available for free download from Cayman Chemical entitled ‘Lipid Nanoparticle Formulation: Basic Concepts & Preparation Procedures‘. Lipid nanoparticles (LNPs) have great potential to revolutionise the development of nucleic acid therapies. Download the Guide to learn more about: The basic concepts and components… Read More
Lipid nanoparticles (LNPs) have great potential to revolutionise the development of nucleic acid therapies. Download the Guide to learn more about: The basic concepts and components of lipid-based drug delivery systems Important considerations for LNP design, stability, and storage Techniques for LNP preparation, characterisation, and functional assessment… Read More
The US Food and Drug Administration (FDA) has granted approval for Alpha Cognition’s Zunveyl (benzgalantamine) previously known as ALPHA-1062, for the treatment of mild-to-moderate Alzheimer’s disease (AD). Tolerability affects therapy adherence, with data showing that 55% of AD patients discontinue their medication after one year, mainly… Read More
There have been a number of key events in the drug discovery community’s diary in 2024 to date, from AACR 2024 and LSX Congress 2024 to SLAS 2024 in Boston and… Read More
The Infection Innovation Consortium: iiCON has launched a new agreement with the Centre of Excellence for Long-Acting Therapeutics (CELT) at the University of Liverpool that will enable iiCON partners and collaborators to access the expertise and capability at CELT. CELT is a research centre focused on the… Read More
EXO Biologics has launched ExoXpert, a contract development and manufacturing organisation (CDMO) specialising in exosomes which offers a mesenchymal stem cells (MSC)-based exosome manufacturing platform used in European clinical trials. During the development of its lead exosome candidate, EXOB-001, Exo Biologics developed ExoPulse, an industrial exosome manufacturing… Read More
A new study will compare whether giving tuberculosis vaccine by inhalation is better at protecting against tuberculosis (TB) than injection into the skin. The Jenner Institute at the University of Oxford is conducting the study using Bacille Calmette-Guérin (BCG), the current licensed vaccine against TB. Read More
This is the latest episode of the free DDW narrated podcast, “Outside the box thinking for drug discovery success”, which covers three written for Volume 23 – Issue 4, Fall 2022 of DDW. They are called: Stanford researchers construct the most complete synthetic microbiome, … Read More
In the In Conversation With series, a part of the free DDW podcast, DDW speaks with members of the drug discovery industry about their work and how it helps turn science into business. In this episode, Megan Thomas is in conversation with Shelley… Read More
