This new Whitepaper, sponsored by ThermoFisher Scientific, explores a scalable workflow for directly visualising LNPs in their near-native state and measuring critical quality attributes to support formulation optimisation, process development, and consistent therapeutic and vaccine delivery. Download now to: See beyond bulk measurements: Learn how cryo-TEM directly visualises individual LNPs in… Read More
Structure-based drugs have two times the rate of clinical success at 50% of preclinical time and cost. A new eBook is now available which highlights recent examples of how cryo-EM and structural insights are being used across various therapeutic modalities to advance drug discovery pipelines. Download this eBook to… Read More
This eBook highlights recent examples of how cryo-EM and structural insights are being used across various therapeutic modalities to advance drug discovery pipelines. Structure-based drugs have two times the rate of clinical success at 50% of preclinical time and cost. Download this eBook to see the impact of cryo-EM on:… Read More
With the use of innovative solubilisation approaches, such as synthetic copolymers, structural biologists can efficiently create soluble membrane proteins optimised for cryo-EM workflows. A new Application Note is now available to download for free, entitled ‘Screening of copolymer nanodiscs with multi-parameter stability characterization on the Prometheus Panta’. In this… Read More
With the use of innovative solubilisation approaches, such as synthetic copolymers, structural biologists can efficiently create soluble membrane proteins optimised for cryo-EM workflows. In this Application Note, learn how to screen for the optimal copolymers using a combination of parameters from the Prometheus Panta instrument for stability characterisation of membrane… Read More
In this webinar, hosted by DDW and supported by Thermo Fisher Scientific, you will learn about the current advancements taking place in antibiotic drug discovery. This event will highlight how cryo-electron microscopy (cryo-EM) can be used to target the lipopolysaccharide transporter MsbA in multidrug-resistant Acinetobacter… Read More
In this webinar, hosted by DDW and supported by Thermo Fisher Scientific, you will learn about the current advancements taking place in antibiotic drug discovery. This event will highlight how cryo-electron microscopy (cryo-EM) can be used to target the lipopolysaccharide transporter MsbA in multidrug-resistant Acinetobacter… Read More
In this webinar, hosted by DDW and supported by Thermo Fisher Scientific, you will learn about the current advancements taking place in antibiotic drug discovery. This event will highlight how cryo-electron microscopy (cryo-EM) can be used to target the lipopolysaccharide transporter MsbA in multidrug-resistant Acinetobacter… Read More
In this webinar, hosted by DDW and supported by Thermo Fisher Scientific, you will learn about the current advancements taking place in antibiotic drug discovery. This event will highlight how cryo-electron microscopy (cryo-EM) can be used to target the lipopolysaccharide transporter MsbA in multidrug-resistant Acinetobacter… Read More
In this webinar, hosted by DDW and supported by Thermo Fisher Scientific, you will learn about the current advancements taking place in antibiotic drug discovery. This webinar highlights how cryo-electron microscopy (cryo-EM) can be used to target the lipopolysaccharide transporter MsbA in multidrug-resistant Acinetobacter baumannii. This pathogen is a major… Read More
In a webinar on 5 September, Professor Susumu Uchiyama, Department of Biotechnology, Graduate School of Engineering, Osaka University, will present his work around adeno-associated virus (AAV) characterisation using cryo-electron microscopy. The event is hosted by DDW and supported by Thermo Fisher Scientific. In… Read More
In a webinar on 5 September, Professor Susumu Uchiyama, Department of Biotechnology, Graduate School of Engineering, Osaka University, will present his work around adeno-associated virus (AAV) characterisation using cryo-electron microscopy. The event is hosted by DDW and supported by Thermo Fisher Scientific. In… Read More
In a webinar on 5 September, Professor Susumu Uchiyama, Department of Biotechnology, Graduate School of Engineering, Osaka University, will present his work around adeno-associated virus (AAV) characterisation using cryo-electron microscopy. The event is hosted by DDW and supported by Thermo Fisher Scientific. In… Read More
In a webinar on 5 September, Professor Susumu Uchiyama, Department of Biotechnology, Graduate School of Engineering, Osaka University, will present his work around adeno-associated virus (AAV) characterisation using cryo-electron microscopy. The event is hosted by DDW and supported by Thermo Fisher Scientific. In… Read More
In this event, Professor Susumu Uchiyama, Department of Biotechnology, Graduate School of Engineering, Osaka University, presents his work around adeno-associated virus (AAV) characterisation using cryo-electron microscopy. In recent years, AAV vectors have been launched and are considered one of the main platforms for gene therapy, with more than 250 clinical… Read More
Salipro Biotech, in collaboration with AstraZeneca, has published data from a study which describes a novel method to directly extract membrane proteins from cells into lipid Salipro nanoparticles, enabling structure-function analysis using surface plasmon resonance (SPR) and cryo-electron microscopy (cryo-EM) for challenging drug targets. The scientists extracted and… Read More
