cryo-microscopy

Salipro Biotech, in collaboration with AstraZeneca, has published data from a study which describes a novel method to directly extract membrane proteins from cells into lipid Salipro nanoparticles, enabling structure-function analysis using surface plasmon resonance (SPR) and cryo-electron microscopy (cryo-EM) for challenging drug targets. The scientists extracted and purified functional membrane proteins directly from cells […]

Scientists have revealed the inner workings of a key protein involved in a wide range of cellular processes – potentially paving the way for better and less toxic cancer drugs.  Using Nobel Prize-winning microscopy techniques, the researchers revealed how the tankyrase protein switches itself on and off by self-assembling into 3D chain-like structures.  Their study, […]

Watch the webinar High resolution electron cryo-microscopy: From membrane proteins to diseases, supported by Thermo Fisher Scientific.  The webinar demonstrates how cryo-EM is impacting high resolution structure biology from membrane proteins to diseases including Alzheimer’s disease and cancer therapeutics by showing high-resolution structures of these proteins bound to inhibitors.  It is presented by Dr Abhay Kotecha, […]

Don’t miss the opportunity to register for this exclusive DDW event High resolution electron cryo-microscopy: From membrane proteins to diseases, supported by Thermo Fisher Scientific. The webinar will take place on 19 October, 2022, 4PM BST, 8AM PDT. Discover how cryo-EM is impacting high resolution structure biology, from membrane proteins to diseases including Alzheimer’s disease and […]

Cryo-EM has been adopted into drug discovery workflows by the pharmaceutical and biotechnology industries having proved itself capable of delivering atomic resolution structures for key targets, including integral membrane proteins such as GPCRs and ion channels.   More recently, significant improvements in throughput have seen use of the technique expand quickly within the sector. Key to […]

Join DDW for a webinar that will demonstrate how cryo-EM is impacting high resolution structure biology from membrane proteins to diseases including Alzheimer’s disease and cancer therapeutics by showing high-resolution structures of these proteins bound to inhibitors.  The exclusive free event High resolution electron cryo-microscopy: From membrane proteins to diseases, supported by Thermo Fisher Scientific, will take […]

Join DDW for this exclusive free event High resolution electron cryo-microscopy: From membrane proteins to diseases, supported by Thermo Fisher Scientific, which will take place on 19 October, 2022, 4PM BST, 8AM PDT. Discover how cryo-EM is impacting high resolution structure biology from membrane proteins to diseases including Alzheimer’s disease and cancer therapeutics by showing high-resolution structures […]

Join DDW for this exclusive free event High resolution electron cryo-microscopy: From membrane proteins to diseases, supported by Thermo Fisher Scientific.   It will take place on 19 October, 2022, 4PM BST, 8AM PDT. Register free here.  The aim of this webinar is to demonstrate how cryo-EM is impacting high resolution structure biology from membrane proteins […]