A new eBook titled ‘Accelerating drug discovery with rational design’ is now available exclusively to DDW readers from Thermo Fisher Scientific. The eBook explores real-world examples demonstrating how high-resolution structural insights can inform earlier decisions, illuminate mechanisms of action, and help reduce the time, cost, and risk associated with advancing… Read More
CRO FairJourney Bio (FJBio) has announced the opening of a cryo-electron microscopy (cryo-EM) structural biology facility in San Diego, California. The new site expands the company’s presence in the US market and incorporates atomic-resolution structural biology directly into its antibody discovery platform. The facility houses… Read More
Structure-based drugs have two times the rate of clinical success at 50% of preclinical time and cost. A new eBook is now available which highlights recent examples of how cryo-EM and structural insights are being used across various therapeutic modalities to advance drug discovery pipelines. Download this eBook to… Read More
This eBook highlights recent examples of how cryo-EM and structural insights are being used across various therapeutic modalities to advance drug discovery pipelines. Structure-based drugs have two times the rate of clinical success at 50% of preclinical time and cost. Download this eBook to see the impact of cryo-EM on:… Read More
With the use of innovative solubilisation approaches, such as synthetic copolymers, structural biologists can efficiently create soluble membrane proteins optimised for cryo-EM workflows. A new Application Note is now available to download for free, entitled ‘Screening of copolymer nanodiscs with multi-parameter stability characterization on the Prometheus Panta’. In this… Read More
With the use of innovative solubilisation approaches, such as synthetic copolymers, structural biologists can efficiently create soluble membrane proteins optimised for cryo-EM workflows. In this Application Note, learn how to screen for the optimal copolymers using a combination of parameters from the Prometheus Panta instrument for stability characterisation of membrane… Read More
In this webinar, hosted by DDW and supported by Thermo Fisher Scientific, you will learn about the current advancements taking place in antibiotic drug discovery. This event will highlight how cryo-electron microscopy (cryo-EM) can be used to target the lipopolysaccharide transporter MsbA in multidrug-resistant Acinetobacter… Read More
In this webinar, hosted by DDW and supported by Thermo Fisher Scientific, you will learn about the current advancements taking place in antibiotic drug discovery. This event will highlight how cryo-electron microscopy (cryo-EM) can be used to target the lipopolysaccharide transporter MsbA in multidrug-resistant Acinetobacter… Read More
In this webinar, hosted by DDW and supported by Thermo Fisher Scientific, you will learn about the current advancements taking place in antibiotic drug discovery. This event will highlight how cryo-electron microscopy (cryo-EM) can be used to target the lipopolysaccharide transporter MsbA in multidrug-resistant Acinetobacter… Read More
In this webinar, hosted by DDW and supported by Thermo Fisher Scientific, you will learn about the current advancements taking place in antibiotic drug discovery. This event will highlight how cryo-electron microscopy (cryo-EM) can be used to target the lipopolysaccharide transporter MsbA in multidrug-resistant Acinetobacter… Read More
Diana Spencer takes a look at two technological developments that have revolutionised the role of imaging in drug discovery. A range of traditional imaging modalities are applied in drug discovery. The development of functional magnetic resonance imaging (MRI), nanoparticles as contrast agents in computerised tomography (CT), ultrafast Doppler for ultrasound… Read More
In this webinar, hosted by DDW and supported by Thermo Fisher Scientific, you will learn about the current advancements taking place in antibiotic drug discovery. This webinar highlights how cryo-electron microscopy (cryo-EM) can be used to target the lipopolysaccharide transporter MsbA in multidrug-resistant Acinetobacter baumannii. This pathogen is a major… Read More
In a webinar on 5 September, Professor Susumu Uchiyama, Department of Biotechnology, Graduate School of Engineering, Osaka University, will present his work around adeno-associated virus (AAV) characterisation using cryo-electron microscopy. The event is hosted by DDW and supported by Thermo Fisher Scientific. In… Read More
In a webinar on 5 September, Professor Susumu Uchiyama, Department of Biotechnology, Graduate School of Engineering, Osaka University, will present his work around adeno-associated virus (AAV) characterisation using cryo-electron microscopy. The event is hosted by DDW and supported by Thermo Fisher Scientific. In… Read More
In a webinar on 5 September, Professor Susumu Uchiyama, Department of Biotechnology, Graduate School of Engineering, Osaka University, will present his work around adeno-associated virus (AAV) characterisation using cryo-electron microscopy. The event is hosted by DDW and supported by Thermo Fisher Scientific. In… Read More
In a webinar on 5 September, Professor Susumu Uchiyama, Department of Biotechnology, Graduate School of Engineering, Osaka University, will present his work around adeno-associated virus (AAV) characterisation using cryo-electron microscopy. The event is hosted by DDW and supported by Thermo Fisher Scientific. In… Read More
