Bacteriophage

#Bacteriophage #Genome editing #Synthetic DNA

New method shows ‘sky’s the limit’ for genome editing 

Scientists have developed a new method to construct bacteriophages with entirely synthetic genetic material, allowing them to edit genomes gene by gene.  Researchers at the University of Pittsburgh, US, led by Graham Hatfull, developed the method to add and subtract genes from the synthetic genome at will. Read More

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Acinetobacter baumannii
#Antibiotic resistance #Antimicrobial resistance (AMR) #Bacteriophage #Phage therapy

Superbug map supports ‘off-the-shelf’ region-specific phage therapies

Scientists have created a global ‘superbug map’ for one of the most dangerous superbug species, Acinetobacter baumannii, which will aid the development of lifesaving bacteriophage (phage) therapies. In a paper published in the journal Cell, an international collaboration led by scientists at the… Read More

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Bacteriophage
#Bacteriophage #Graft vs Host Disease #Japan #Phage therapy #Stem cell transplant

Bacteriophage study offers new hope in treating GVHD

Researchers from Japan have identified a bacteriophage-derived enzyme that holds promise for future applications in preventing or treating acute graft-versus-host disease (aGVHD). Acute GVHD is a medical condition that occurs when donor immune cells attack the recipient’s tissues after an allogeneic hematopoietic stem cell transplantation (allo-HCT). Read More

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Bacteria
#Antibiotics #Antimicrobial resistance (AMR) #Bacteria #Bacteriophage #ETH Zurich

Swiss scientists identify a virus that kills dormant bacteria

Researchers have found a virus that kills dormant bacteria, a discovery that could help to combat infections that can’t be treated with antibiotics. For the first time, ETH Zurich researchers in Switzerland have isolated a bacteriophage from rotting plant material that can attack and kill bacteria… Read More

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