Antimicrobial resistance (AMR)

The UK government will invest up to £39 ($48) million in antimicrobial resistance (AMR) research through the Global AMR Innovation Fund (GAMRIF). The funding includes up to £25 ($30.9) million awarded to support the early development of new antibiotics, vaccines, rapid diagnostics and other products to combat life-threatening drug-resistant infections. The money will bolster the […]

The United States Patent and Trademark Office (USPTO) has granted Gedea Biotech’s patent application 16/753,899 directed to gluconic acid derivatives for preventing and/or treating bacterial infections. The patent can be kept in force until 2038. The specific derivative Glucone-delta lactone (GDL) in pHyph is a well-documented substance with a low risk of developing antimicrobial resistance. […]

University of Queensland (UQ) researchers have led a national study on the four main bacteria that cause sepsis, providing new targets for developing antibiotics. Professor Mark Walker and Professor Mark Schembri from UQ’s Institute for Molecular Bioscience, along with Dr Andre Mu from the University of Melbourne and teams from 23 research organisations around Australia, […]

UK-based Cystic fibrosis (CF) Syndicate in Antimicrobial Resistance (AMR) has announced a £3 million ($3.6 million) Collaborative Discovery Programme for drug discovery innovators to accelerate the development of new treatments for people with CF. Funded by UK medical research charity LifeArc, the programme will support approximately five collaborative projects that aim to rapidly identify new […]

The Global Antibiotic Research and Development Partnership (GARDP) and the University of Liverpool have confirmed an agreement to collaborate on new projects to address antimicrobial resistance (AMR) for the benefit of public health. Since 2018, GARDP and the University of Liverpool have been working together to advance new treatment options for new-borns with sepsis. Their […]

For the first time, researchers have developed an mRNA vaccine that is 100% effective against a type of bacteria that is lethal to humans, paving the way for effective vaccination against antibiotic-resistant bacteria. The study, conducted in an animal model, demonstrated that all treated animals were fully protected against the bacteria. According to the researchers, […]

Researchers have found a range of commonly prescribed antidepressants can increase bacteria’s resistance to antibiotic medications. A study led by Professor Jianhua Guo from University of Queensland’s Australian Centre for Water and Environmental Biotechnology focused on prescription drugs used to treat depressive disorders, anxiety disorders, and other psychological conditions.  More than 42 million prescriptions were […]

A major boost of £1.76 million ($2.16 million) will fund research designed to stop antibiotics failing, to help mitigate the rising threat of antibiotic resistance.  Professor Stefano Pagliara, at the University of Exeter, has received the award to advance his work on controlling the processes and biological mechanisms that cause antibiotics to fail, and can […]

Vésale Bioscience, a company in the research and development of solutions and treatments using phage therapy for multi-resistant infections, has received €1.8 million in grants from the European Innovation Council (EIC) Accelerator Fund for its PhageDiag project.  The project is a phagogram using artificial intelligence (AI) that enables decentralised diagnostics and personalised treatment. According to […]

Cresset Discovery and the University of Exeter have entered a collaboration to discovery novel antimicrobial drugs.  Cresset Discovery will use virtual screening to identify promising new candidates, building on research led by Dr Stefano Pagliara.  Virtual screening enables chemists to explore new chemical space, discover diverse chemotypes and generate new IP.  Antimicrobials play a fundamental […]