Daniel Delubac, Chief Executive Officer at iOrganBio looks at how technologies that mimic human behaviour can improve drug discovery efforts past animal models. The US is signalling a decisive shift toward human-based drug discovery. In March, the National Institutes… Read More
The European Commission has said it is “firmly committed to phasing out animal testing” as it launches a roadmap for chemical safety assessments. The latest statistics on animal use for the EU and Norway show over 9.1 million animals were used in scientific tests and experiments in the EU and Norway in 2023. This includes… Read More
Professor Mark Lewis, CEO of Myomaker Bio explores how animal testing is being reduced through a new era of drug development. Across the world, there is growing evidence that the long-standing reliance on animal testing in scientific research could be entering a period of significant change. For decades, scientists, regulators and… Read More
How can we leverage canine osteosarcoma to validate biomarkers and accelerate the pathway to new therapies? Integration of comparative biology, specifically the study of naturally occurring cancers in companion animals (primarily dogs) known as comparative oncology, over the last three decades has significantly transformed cancer research… Read More
The latest episode of the DDW Highlights Podcast is now available to listen to below. DDW’s Bruno Quinney narrates five key stories of the previous week to keep DDW subscribers up-to-date on the latest industry news. Last week, groundbreaking research showed the Covid-19 mRNA vaccine could boost cancer response. Elsewhere,… Read More
News round-up for 10 – 14 November by Bruno Quinney, Content Team at DDW. This week’s top story comes from groundbreaking research showing the Covid-19 mRNA vaccine boosts the immune system’s cancer response. The theme of UK investment dominates other headlines, while a report shows an effective… Read More
A new UK initiative is aiming to transform human-based research models to provide better understanding of disease and accelerate new medicines. The UKRI Medical Research Council (MRC), Wellcome and UKRI Innovate UK committed a joint £15.9 million ($20.9 million) investment to develop advanced, specific and highly reproducible… Read More
DDW Editor Reece Armstrong takes a look at three pieces of animal model research that are driving forward drug discovery. Animal models have been used as standard tools for clinical research for decades now, helping researchers bring treatments to market. Though the models have faced challenges in translating results seen… Read More
Dr Isaac Bentwich, Founder and CEO of Quris-AI examines the rise of alternative approaches to animal testing within drug discovery. Since the Federal Food, Drug, and Cosmetic Act of 1938, animal testing has served as the foundational model for biomedical research, offering scientists insights into disease mechanisms and drug safety. Read More
This advertorial for Taconic appeared in DDW Volume 26 – Issue 2, Spring 2025 Read the digital issue Taconic in vivo models provide enhanced physiological relevance for translational research. The NOG portfolio offers severely immunodeficient mice enabling engraftment of human hematopoietic stem cells (HSCs) to recapitulate features of the… Read More
A new Whitepaper from Taconic Biosciences is now available to download entitled ‘An Introduction to Humanized Immune System Mouse Models‘. Traditional mouse models have limitations in recapitulating human biology — but humanised immune system (HIS) mice offer a more predictive approach. These advanced models bring you closer to clinical… Read More
Unlock the power of humanised immune system mice. Traditional mouse models have limitations in recapitulating human biology — but humanised immune system (HIS) mice offer a more predictive approach. These advanced models bring you closer to clinical relevance. Download this Whitepaper to discover: The evolution of immunodeficient mice Key humanisation… Read More
The latest sponsored DDW Sitting Down With vodcast features Michael Ellis, Senior Director of R&D at The Jackson Laboratory (JAX), and Timothy Robertson, CEO of TLR Ventures and Leader of the Digital In Vivo Alliance to introduce their new digital home cage monitoring system, Envision. Both Ellis and… Read More
DDW’s Multimedia Editor Megan Thomas attended the Society for Neuroscience (SfN)’s Neuroscience 2024 in October 2024 in Chicago, US. Having published a general event roundup, here she unpacks the ‘Animals in Research’ panel: Lifesaving clinical advances stemming from animal research, which took place on Monday 7 October. Read More
NRG Therapeutics has been awarded a non-dilutive grant from Target ALS Foundation to support its discovery programme for amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease or motor neurone disease. It is one of five recipients of the 2024 In Vivo Target Validation grants… Read More
Professor Andy Whiting, CEO of Nevrargenics, asks whether animal models should be used as the default regulatory requirement and explores the times to use them. Animal models (AMs) have generally been seen as useful for drug development and biomedical research for many years. They are assumed to closely mimic human… Read More
