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        Alnylam Pharmaceuticals

        Patient using blood pressure monitor

        Positive Phase I results for RNAi therapeutic in hypertension

        25 July 2023

        Alnylam Pharmaceuticals has revealed results from its Phase I study of zilebesiran, an investigational RNAi therapeutic targeting liver-expressed angiotensinogen (AGT) in development for the treatment of hypertension. The results are published in the New England Journal of Medicine (NEJM). The key data showed that compared to placebo, zilebesiran was associated with dose-dependent reductions in serum […]

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