Targeting Energy Metabolism for Cancer Therapeutic Discovery using Agilent Seahorse XF Technology
This white paper discusses targeting energy metabolism for cancer therapeutic discovery using Agilent Seahorse XF technology.
Altered energy metabolism is a well-established hallmark of cancer. Examination of energy production rates and pathways in live cells has been used to identify and validate potential druggable targets. By measuring bioenergetic phenotype, ATP production rate, mitochondrial, and glycolytic function novel strategies for targeting various cancers are revealed.
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