Combinatorial chemistry

Recent Developments in Combinatorial Chemistry By Dr Anthony D Baxter Combinatorial chemistry has advanced significantly from the early 1990s when it was a new science of mainly conceptual interest to today where it has evolved into a key component of the drug discovery industry. The needs of the Pharma industry have demanded that compound libraries […]

HTS a strategy for drug discovery By Dr AR Knight, Cerebrus Ltd Whichever technologies are implemented, high throughput screening is set to become one of the cornerstones of drug discovery, however deciding which strategy to implement will provide many headaches. This article concentrates on screens identifying the interaction of small molecules with protein targets rather […]

Plants as a source of new medicines By Jennie Gwynn and Peter J Hylands Putting aside the excitement surrounding the human genome, in the near future we may well start to see the emergence of a new class of prescription medicine containing complex mixtures of plant extracts. This article discusses the important role that plants […]