The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. This week started with World Diabetes Day on 14 November and concluded… Read More
News round-up for 14-18 November by DDW Digital Content Editor Diana Spencer. This week started with World Diabetes Day on 14 November and concluded with the start of World Antimicrobial Awareness Week, which aims to improve education and understanding of the growing issue of antimicrobial resistance. … Read More
Scientists from Oxford University and the University of Birmingham have made the first bone marrow ‘organoids’ that include all the key components of human marrow. The technology allows for the screening of multiple anti-cancer drugs at the same time, as well as testing personalised treatments for individual… Read More
This is the latest episode of the free DDW podcast, “The next steps in the fight against cancer”. It covers two articles written for Volume 22, Issue 4 – Fall 2021 of DDW. They are called “Accelerating research: the path forward for treating rare cancers” and “Inside combination… Read More
New research has found variable voltages in the membranes of breast cancer cells, revealing clues about how they grow and spread. The study, led by Imperial College London and The Institute of Cancer Research, London, could help us better understand how cancer cells ‘decide’ when to multiply and where to… Read More
DynamiCure has dosed the first patients in its Phase I clinical trial evaluating the first of the company’s two anti-CD93 monoclonal antibody candidates, DCBY02, in adults with a wide range of advanced cancers. CD93 is a novel target downstream of VEGF-A (vascular endothelial growth factor) that has been shown… Read More
An experimental therapeutic cancer vaccine induced immune system responses that led to significant tumour regression in mice, according to investigators from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. The researchers found that intravenous (IV) administration of the vaccine… Read More
The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. This week we learned the shocking statistic that… Read More
New research about how cancer-related proteins bind copper ions opens up potential new drug targets to treat cancer. Studies have shown that the level of copper in tumour cells and blood serum from cancer patients is elevated, and the conclusion is that cancer cells need more copper… Read More
News round-up for 7-11 November by DDW Digital Content Editor Diana Spencer This week we learned the shocking statistic that a third of scientific researchers have, or know a close colleague who has, experienced abuse after posting research online. It wasn’t all bad news, however, as top… Read More
Immutep has revealed encouraging initial clinical data from two trials investigating its lead product candidate eftilagimod alpha in non-small-cell lung cancer. Findings from the trials were shared at the Society for Immunotherapy of Cancer (SITC) Annual Meeting 2022. The INSIGHT-003 trial is evaluating eftilagimod alpha… Read More
Merck has exercised its option to jointly develop and commercialise personalised cancer vaccine (PCV) mRNA-4157/V940 pursuant to the terms of its existing collaboration and license agreement with Moderna. mRNA-4157/V940 is currently being evaluated in combination with KEYTRUDA, Merck’s anti-PD-1 therapy, as adjuvant treatment for patients with high-risk… Read More
Scientists have uncovered a critical feature that a promising new class of cancer drugs, known as CELMoDs, needs to be effective. CELMoDs are designed to attack cancer by binding to a regulatory protein called cereblon, which then triggers the degradation of key cancer-driving proteins. In… Read More
An update on the latest oncology developments by DDW Digital Content Editor Diana Spencer The last month has seen huge strides forward in our understanding of cancers, particularly in how they develop resistance to therapies and how we can ‘outsmart’ them using gene editing or different therapeutic pathways, but also… Read More
A team from the University of Geneva (UNIGE) has found a way to overcome chemotherapy resistance in colorectal cancer. The team successfully used a combination of tyrosine kinase inhibitors, opening up new avenues for developing therapies that are more targeted than chemotherapy. Colorectal cancer is… Read More
News round-up for 24-28 October by DDW Digital Content Editor Diana Spencer Over the last seven days we’ve seen discoveries that could lead to new treatments for Covid-19, pancreatic cancer and Epstein-Barr virus, as well as the launch of the UK’s largest health research programme and the innovative application of… Read More
