RESULTS FOR : 'Genomics'
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Metabolomics - A Playbook for Functional Genomics

If we have learned anything from scientific research in the last 20 years, it is that finding cures to complex diseases is difficult. Despite the promise of the genomic revolution, disease progression and patient outcomes are still not easily predicted by genetic factors alone.

Editing the Human Genome: Role in Functional Genomics and Translational Medicine

It is now readily accepted that we are in a post genomic era. With the steady flow of genomic information available to researchers worldwide, the focus turns to ways to analyse this information effectively and then utilise it in a practical manner.

TOXICOGENOMICS insights into the present and future. Winter 01

Adverse drug responses are an important post-marketing public health issue, occurring many times in subsets of treatment populations. Promising new approaches to predicting physiological responses to drugs are focused on genomic responses or toxicogenomics1. This article provides a current perspective on toxicogenomics technologies that are aimed at: 1) providing new tools and systems for more rapid, accurate and complete toxicity assessments in advance of human exposure; 2) enhancing the thoroughness and accuracy of toxicity assessments achievable with currently available test systems, and 3) predictive assessments of individualised risk for developing adverse drug reactions.

High throughput genomics and drug discovery - parallel universes or a continuum? Summer 02

HTS has been in place for approximately 10-12 years and has achieved a threeorder of magnitude scale up. Genomics has been in a 'high throughput' mode for approximately four years for areas such as genotyping, is an emerging field governed by sporadic technology leaps and data generation leaps. However, despite these approaches, there are many discrepancies and parallels that exist between the two areas: sample management/assay assembly/parallel processing/ data analysis. However, some differences exist with respect to regulatory issues, public perception and ethical consent. The article will compare and contrast these fields and highlight where both disciplines may learn from each other

High throughput genomics and drug discovery - parallel universes or a continuum? Summer 02

HTS has been in place for approximately 10-12 years and has achieved a threeorder of magnitude scale up. Genomics has been in a 'high throughput' mode for approximately four years for areas such as genotyping, is an emerging field governed by sporadic technology leaps and data generation leaps. However, despite these approaches, there are many discrepancies and parallels that exist between the two areas: sample management/assay assembly/parallel processing/ data analysis. However, some differences exist with respect to regulatory issues, public perception and ethical consent. The article will compare and contrast these fields and highlight where both disciplines may learn from each other.

Tools for STRUCTURAL GENOMICS accelerating the structure pipeline. Summer 04

The international structural genomics effort has resulted in a number of technological advancements that are accelerating the process of threedimensional structure determination while continually decreasing the cost per structure.

STRUCTURAL Genomics drives demand for high throughput protein purification. Fall 04

The rapid growth in proteomic and structural and functional genomic research is driving demand for purified proteins that far exceeds the industry�s ability to scale-up conventional protein production technologies. This demand has sparked innovation in protein separation and purification technologies. We discuss how the advent of improved systems for protein expression and high throughput parallel protein purification can deliver the opportunity to ignite a revolution in structural and functional genomics, proteomics and high-value drug target discovery.